Iron overload impairs normal hematopoietic stem and progenitor cells through reactive oxygen species and shortens survival in myelodysplastic syndrome mice

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Iron overload impairs normal hematopoietic stem and progenitor cells through reactive oxygen species and shortens survival in myelodysplastic syndrome mice

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http://www.wikidata.org/entity/Q58793901

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im Oktober 2018 veröffentlichter wissenschaftlicher Artikel

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wetenschappelijk artikel

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наукова стаття, опублікована в жовтні 2018

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Iron overload impairs normal h ...... myelodysplastic syndrome mice

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Iron overload impairs normal h ...... myelodysplastic syndrome mice

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Iron overload impairs normal h ...... myelodysplastic syndrome mice

@en

Iron overload impairs normal h ...... myelodysplastic syndrome mice

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Iron overload impairs normal h ...... myelodysplastic syndrome mice

@en

Iron overload impairs normal h ...... myelodysplastic syndrome mice

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P1476

Iron overload impairs normal h ...... myelodysplastic syndrome mice

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Hongyan Ni

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Juanxia Meng

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Luqiao Wang

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Mingfeng Zhao

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Ping Xu

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Rui Cui

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Songnan Sui

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Wenyi Lu

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Xiaoli Cao

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Xiaoyuan He

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P2860

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Decision points in the treatment of transfusional iron overload in patients with myelodysplastic syndromes: why, when, and how to chelate.

An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia.

Effects of iron overload on the bone marrow microenvironment in mice

ROS-mediated iron overload injures the hematopoiesis of bone marrow by damaging hematopoietic stem/progenitor cells in mice.

Meis1 preserves hematopoietic stem cells in mice by limiting oxidative stress.

Novel players in β-thalassemia dyserythropoiesis and new therapeutic strategies.

Reactive oxygen species mediated T lymphocyte abnormalities in an iron-overloaded mouse model and iron-overloaded patients with myelodysplastic syndromes.

Role of RUNX1 in hematological malignancies.

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1627-1634

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scholarly article

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10.3324/HAEMATOL.2018.193128

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English

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103

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2018-10-01T00:00:00Z

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29903757

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hematology

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6165791

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