Selection of Antibodies with Tailored Properties by Application of High-Throughput Multiparameter Fluorescence-Activated Cell Sorting of Yeast-Displayed Immune Libraries

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Selection of Antibodies with Tailored Properties by Application of High-Throughput Multiparameter Fluorescence-Activated Cell Sorting of Yeast-Displayed Immune Libraries

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wetenschappelijk artikel

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наукова стаття, опублікована в жовтні 2018

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name

Selection of Antibodies with T ...... ast-Displayed Immune Libraries

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Selection of Antibodies with T ...... ast-Displayed Immune Libraries

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Selection of Antibodies with T ...... ast-Displayed Immune Libraries

@en

Selection of Antibodies with T ...... ast-Displayed Immune Libraries

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Selection of Antibodies with T ...... ast-Displayed Immune Libraries

@en

Selection of Antibodies with T ...... ast-Displayed Immune Libraries

@nl

P1476

Selection of Antibodies with T ...... ast-Displayed Immune Libraries

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P2093

Achim Doerner

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Björn Hock

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Christian Schröter

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Harald Kolmar

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Jan Beck

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Lars Toleikis

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Laura Rhiel

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Ralf Günther

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Simon Krah

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Stefan Becker

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P2860

Knockout rats via embryo microinjection of zinc-finger nucleases

Continuous cultures of fused cells secreting antibody of predefined specificity

Human antibody production in transgenic animals

Yeast mating for combinatorial Fab library generation and surface display

Introducing antigen-binding sites in structural loops of immunoglobulin constant domains: Fc fragments with engineered HER2/neu-binding sites and antibody properties

High-affinity IgG antibodies develop naturally in Ig-knockout rats carrying germline human IgH/Igκ/Igλ loci bearing the rat CH region

Construction and diversification of yeast cell surface displayed libraries by yeast mating: application to the affinity maturation of Fab antibody fragments.

From rodent reagents to human therapeutics using antibody guided selection.

Selecting and screening recombinant antibody libraries.

Affinity maturation of phage display antibody populations using ribosome display.

P2888

s12033-018-0109-0

P304

727-735

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scholarly article

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10.1007/S12033-018-0109-0

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P407

English

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P478

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P577

2018-10-01T00:00:00Z

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P698

30076531

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P921

bioengineering

biotechnology

molecular biology

P932

6132741

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