Construction and diversification of yeast cell surface displayed libraries by yeast mating: application to the affinity maturation of Fab antibody fragments.
about
Cross-Neutralising Nanobodies Bind to a Conserved Pocket in the Hemagglutinin Stem Region Identified Using Yeast Display and Deep Mutational Scanning.Isolation of anti-CD22 Fv with high affinity by Fv display on human cells.Optimizing the affinity and specificity of proteins with molecular display.Design of synthetic antibody libraries.A decade of yeast surface display technology: where are we now?Efficient recovery of high-affinity antibodies from a single-chain Fab yeast display library.Engineering of stable bispecific antibodies targeting IL-17A and IL-23.Affinity maturation of human botulinum neurotoxin antibodies by light chain shuffling via yeast mating.Mining human antibody repertoires.Rapid isolation of high-affinity human antibodies against the tumor vascular marker Endosialin/TEM1, using a paired yeast-display/secretory scFv library platform.Human monoclonal antibody fragments binding to insulin-like growth factors I and II with picomolar affinity.Human anti-EGFL7 recombinant full-length antibodies selected from a mammalian cell-based antibody display library.Affinity maturation of antiHER2 monoclonal antibody MIL5 using an epitope-specific synthetic phage library by computational design.Addressing polyspecificity of antibodies selected from an in vitro yeast presentation system: a FACS-based, high-throughput selection and analytical tool.Therapeutic antibody engineering by high efficiency cell screening.REAL-Select: full-length antibody display and library screening by surface capture on yeast cells.Five birds, one stone: neutralization of α-hemolysin and 4 bi-component leukocidins of Staphylococcus aureus with a single human monoclonal antibody.Efficient construct of a large and functional scFv yeast display library derived from the ascites B cells of ovarian cancer patients by three-fragment transformation-associated recombination.Selection of Recombinant Human Antibodies.Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies.Integrated mimicry of B cell antibody mutagenesis using yeast homologous recombinationA Single-Chain Antibody Using LoxP511 as the Linker Enables Large-Content Phage Library Construction via Cre/LoxP Recombination.Assessing the function of pneumococcal neuraminidases NanA, NanB and NanC in in vitro and in vivo lung infection models using monoclonal antibodiesSelection of Antibodies with Tailored Properties by Application of High-Throughput Multiparameter Fluorescence-Activated Cell Sorting of Yeast-Displayed Immune Libraries
P2860
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P2860
Construction and diversification of yeast cell surface displayed libraries by yeast mating: application to the affinity maturation of Fab antibody fragments.
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Construction and diversificati ...... ion of Fab antibody fragments.
@ast
Construction and diversificati ...... ion of Fab antibody fragments.
@en
type
label
Construction and diversificati ...... ion of Fab antibody fragments.
@ast
Construction and diversificati ...... ion of Fab antibody fragments.
@en
prefLabel
Construction and diversificati ...... ion of Fab antibody fragments.
@ast
Construction and diversificati ...... ion of Fab antibody fragments.
@en
P2093
P1433
P1476
Construction and diversificati ...... ion of Fab antibody fragments.
@en
P2093
Anita Wehnert
Hennie R Hoogenboom
Lydia Blaise
Mieke P G Steukers
Simon E Hufton
Twan van den Beucken
P304
P356
10.1016/J.GENE.2004.08.014
P407
P577
2004-11-01T00:00:00Z