about
ABC transporters in the protozoan parasite Leishmania.LABCG2, a new ABC transporter implicated in phosphatidylserine exposure, is involved in the infectivity and pathogenicity of LeishmaniaCombination of suboptimal doses of inhibitors targeting different domains of LtrMDR1 efficiently overcomes resistance of Leishmania spp. to Miltefosine by inhibiting drug effluxTyrosol and hydroxytyrosol derivatives as antitrypanosomal and antileishmanial agents.The Oral Antimalarial Drug Tafenoquine Shows Activity against Trypanosoma brucei.LmABCB3, an atypical mitochondrial ABC transporter essential for Leishmania major virulence, acts in heme and cytosolic iron/sulfur clusters biogenesis.A new ATP-binding cassette protein is involved in intracellular haem trafficking in Leishmania.Insect cell versus bacterial overexpressed membrane proteins: an example, the human ABCG2 transporter.Flavonoid structure-activity studies identify 6-prenylchrysin and tectochrysin as potent and specific inhibitors of breast cancer resistance protein ABCG2.Altered drug membrane permeability in a multidrug-resistant Leishmania tropica line.Characterization of an ABCG-like transporter from the protozoan parasite Leishmania with a role in drug resistance and transbilayer lipid movement.Increased glycolytic ATP synthesis is associated with tafenoquine resistance in Leishmania majorCelastraceae sesquiterpenes as a new class of modulators that bind specifically to human P-glycoprotein and reverse cellular multidrug resistance.Sitamaquine overcomes ABC-mediated resistance to miltefosine and antimony in Leishmania.Sitamaquine sensitivity in Leishmania species is not mediated by drug accumulation in acidocalcisomes.G-Quadruplex Identification in the Genome of Protozoan Parasites Points to Naphthalene Diimide Ligands as New Antiparasitic Agents.Synthesis, Binding Properties, and Differences in Cell Uptake of G-Quadruplex Ligands Based on Carbohydrate Naphthalene Diimide Conjugates.The overexpression of a new ABC transporter in Leishmania is related to phospholipid trafficking and reduced infectivity.Trypanosomatid parasites rescue heme from endocytosed hemoglobin through lysosomal HRG transporters.Autophagic-related cell death of Trypanosoma brucei induced by bacteriocin AS-48.New Natural Sesquiterpenes as Modulators of Daunomycin Resistance in a Multidrug-ResistantLeishmaniatropicaLine‖,⊥Potent competitive inhibition of drug binding to the Saccharomyces cerevisiae ABC exporter Pdr5p by the hydrophobic estradiol-derivative RU49953Carbohydrate-naphthalene diimide conjugates as potential antiparasitic drugs: Synthesis, evaluation and structure-activity studiesSemisynthesis of ω-Hydroxyalkylcarbonate Derivatives of Hydroxytyrosol as Antitrypanosome AgentsLeishmania heme uptake involves LmFLVCRb, a novel porphyrin transporter essential for the parasite
P50
Q34512513-CB9D989E-6EB9-47A5-A95A-076B1CBA679FQ34702464-46C4116B-33E1-42EC-9D24-E432036CB9A7Q35023368-30644D1A-9F11-4594-9A75-8F7B564D8959Q36011483-413346A1-22E3-4464-8AA3-AF5C361B6780Q36076081-F519CD30-BD45-4725-9A49-8DD884F1E431Q36428337-F94D3D5C-7AA4-4C71-A93B-0B8EDBF42E70Q39604692-E5541CBC-1806-4364-B669-4CAACB044511Q39674739-027F0041-427E-47B4-9813-C20207760FDFQ40414468-8F16B711-44E2-428C-AC2E-88ECE1B33087Q41068562-C8306652-79A0-419C-BE3A-7E1EB9A39D13Q41940537-DE186D80-D572-4D39-8FAC-B5EC60E6412DQ41984797-C90BB402-FB78-4ED0-85BF-2164C523F840Q42824914-7520E9D8-B3AB-4250-A1F4-3FA0A5903545Q42849844-7A1111D3-AB41-4164-93A8-4E681EA91149Q42917206-FCCEB2FA-BA51-4DD6-9E0E-C9C06480A0FBQ47555422-3D012CAA-1702-46EA-AEF5-5657402D792CQ48176921-E8FA040A-FA3A-453B-919D-B8BD358C3F67Q48243238-63E94956-839B-4936-AE6C-43D13C8EA14BQ51690155-C768CB75-70B1-49AB-89FA-9B4AA19EB6C3Q53693383-68DB5931-A108-45CB-BB00-2442590B48A1Q58854497-050B6838-174D-431F-B34F-EE83E3B03836Q73745592-85645C0F-DA4C-45E4-9B0B-7FAB8144A987Q90026431-76BB5B4B-9BD6-4C22-9E81-7A93604EB029Q91222292-7498968F-B3DD-4156-95C6-A9A97E06298CQ92358916-C95D9F47-1D15-4063-ABC2-A755D3792857
P50
description
researcher ORCID ID = 0000-0003-0552-5837
@en
wetenschapper
@nl
name
José María Pérez-Victoria
@ast
José María Pérez-Victoria
@en
José María Pérez-Victoria
@es
José María Pérez-Victoria
@nl
type
label
José María Pérez-Victoria
@ast
José María Pérez-Victoria
@en
José María Pérez-Victoria
@es
José María Pérez-Victoria
@nl
prefLabel
José María Pérez-Victoria
@ast
José María Pérez-Victoria
@en
José María Pérez-Victoria
@es
José María Pérez-Victoria
@nl
P106
P1153
6602363614
P21
P31
P496
0000-0003-0552-5837