Combination of suboptimal doses of inhibitors targeting different domains of LtrMDR1 efficiently overcomes resistance of Leishmania spp. to Miltefosine by inhibiting drug efflux - Wikidata - awgldk - TriplyDB

Combination of suboptimal doses of inhibitors targeting different domains of LtrMDR1 efficiently overcomes resistance of Leishmania spp. to Miltefosine by inhibiting drug efflux

Combination of suboptimal doses of inhibitors targeting different domains of LtrMDR1 efficiently overcomes resistance of Leishmania spp. to Miltefosine by inhibiting drug efflux

http://www.wikidata.org/entity/Q35023368

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New Approaches to Overcome Transport Related Drug Resistance in Trypanosomatid Parasites Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis Different Mutations in a P-type ATPase Transporter in Leishmania Parasites are Associated with Cross-resistance to Two Leading Drugs by Distinct Mechanisms Metabolic reconstruction identifies strain-specific regulation of virulence in Toxoplasma gondii.Use of antimony in the treatment of leishmaniasis: current status and future directions.Therapeutic switching in leishmania chemotherapy: a distinct approach towards unsatisfied treatment needs.The Oral Antimalarial Drug Tafenoquine Shows Activity against Trypanosoma brucei.Drug resistance in visceral leishmaniasis.Untargeted metabolomic analysis of miltefosine action in Leishmania infantum reveals changes to the internal lipid metabolism.A new ATP-binding cassette protein is involved in intracellular haem trafficking in Leishmania.Characterization of an ABCG-like transporter from the protozoan parasite Leishmania with a role in drug resistance and transbilayer lipid movement.Sitamaquine overcomes ABC-mediated resistance to miltefosine and antimony in Leishmania.Autophagic-related cell death of Trypanosoma brucei induced by bacteriocin AS-48.Joining forces: first application of a rapamycin-induced dimerizable Cre system for conditional null mutant analysis in Leishmania.Transporters in Anti-Parasitic Drug Development and Resistance

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P2860

Combination of suboptimal doses of inhibitors targeting different domains of LtrMDR1 efficiently overcomes resistance of Leishmania spp. to Miltefosine by inhibiting drug efflux

http://www.wikidata.org/entity/Q35023368

description

2006 nî lūn-bûn

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2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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Combination of suboptimal dose ...... sine by inhibiting drug efflux

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Combination of suboptimal dose ...... sine by inhibiting drug efflux

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Combination of suboptimal dose ...... sine by inhibiting drug efflux

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Combination of suboptimal dose ...... sine by inhibiting drug efflux

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Combination of suboptimal dose ...... sine by inhibiting drug efflux

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Combination of suboptimal dose ...... sine by inhibiting drug efflux

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Antimicrobial Agents and Chemotherapy

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Combination of suboptimal dose ...... sine by inhibiting drug efflux

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Adriana Parodi-Talice

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Attilio Di Pietro

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Boris I Bavchvarov

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Denis Barron

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F Javier Pérez-Victoria

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Fernando Cortés-Selva

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Francisco Muñoz-Martínez

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M Paola Costi

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Mathias Maitrejean

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Santiago Castanys

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P2860

Crystal structure of the Src family tyrosine kinase Hck

ABC transporters: from microorganisms to man

Multidrug resistance in Leishmania donovani is conferred by amplification of a gene homologous to the mammalian mdr1 gene

Reversal of multidrug resistance by the P-glycoprotein modulator, LY335979, from the bench to the clinic.

A phase I and pharmacologic study of the MDR converter GF120918 in combination with doxorubicin in patients with advanced solid tumors.

Biochemical, cellular, and pharmacological aspects of the multidrug transporter.

P-glycoprotein-mediated resistance to chemotherapy in cancer cells: using recombinant cytosolic domains to establish structure-function relationships.

Multiple recognition of various amphiphilic molecules by the multidrug resistance P-glycoprotein: molecular mechanisms and pharmacological consequences coming from functional interactions between various drugs.

High-affinity binding of silybin derivatives to the nucleotide-binding domain of a Leishmania tropica P-glycoprotein-like transporter and chemosensitization of a multidrug-resistant parasite to daunomycin.

A human cell line from a pleural effusion derived from a breast carcinoma.

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3102-3110

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10.1128/AAC.00423-06

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9

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50

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Francisco Gamarro

José María Pérez-Victoria

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16940108

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