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Antioxidant treatment for amyotrophic lateral sclerosis or motor neuron diseaseAntioxidant treatment for amyotrophic lateral sclerosis / motor neuron diseaseThe copper chaperone CCS directly interacts with copper/zinc superoxide dismutaseThe copper chaperone for superoxide dismutaseThe Dual Function of Reactive Oxygen/Nitrogen Species in Bioenergetics and Cell Death: The Role of ATP SynthaseRedox regulation in amyotrophic lateral sclerosisDestabilizing protein polymorphisms in the genetic background direct phenotypic expression of mutant SOD1 toxicityPathophysiological Role of Peroxynitrite Induced DNA Damage in Human Diseases: A Special Focus on Poly(ADP-ribose) Polymerase (PARP)Copper chaperone for superoxide dismutase is essential to activate mammalian Cu/Zn superoxide dismutaseRemarkable increase in cerebrospinal fluid 3-nitrotyrosine in patients with sporadic amyotrophic lateral sclerosisReactive nitrogen species in cellular signalingParadoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health ImplicationsPeroxynitrite rapidly permeates phospholipid membranesS-Nitrosylation of p47(phox) enhances phosphorylation by casein kinase 2.Protein nitration in a mouse model of familial amyotrophic lateral sclerosis: possible multifunctional role in the pathogenesis.Motor neurons rapidly accumulate DNA single-strand breaks after in vitro exposure to nitric oxide and peroxynitrite and in vivo axotomy.Immunohistochemical analysis of oxidative stress and DNA repair proteins in normal mammary and breast cancer tissues.Nitric oxide-mediated oxidative damage and the progressive demise of motor neurons in ALS.Pathological aspects of lipid peroxidation.Role of oxidative stress and antioxidants in neurodegenerative diseases.Nitrotyrosine formation and its role in various pathological conditions.Aggregation propensities of superoxide dismutase G93 hotspot mutants mirror ALS clinical phenotypesMitochondrial and Cell Death Mechanisms in Neurodegenerative Diseases.The essential nutrient pyrroloquinoline quinone may act as a neuroprotectant by suppressing peroxynitrite formation.Familial amyotrophic lateral sclerosis.A systematic review of antioxidant treatment for amyotrophic lateral sclerosis/motor neuron disease.Confirmatory double-blind, parallel-group, placebo-controlled study of efficacy and safety of edaravone (MCI-186) in amyotrophic lateral sclerosis patientsTherapeutic developments in the treatment of amyotrophic lateral sclerosis.The role of immunophilins in mutant superoxide dismutase-1linked familial amyotrophic lateral sclerosis.The decomposition of peroxynitrite to nitroxyl anion (NO-) and singlet oxygen in aqueous solutionAmyotrophic lateral sclerosis: a novel hypothesis involving a gained 'loss of function' in the JNK/SAPK pathway.Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II) (CuII(atsm)) protects against peroxynitrite-induced nitrosative damage and prolongs survival in amyotrophic lateral sclerosis mouse model.Relevance of oxidative injury in the pathogenesis of motor neuron diseases.Dietary Vitamin D3 Restriction Exacerbates Disease Pathophysiology in the Spinal Cord of the G93A Mouse Model of Amyotrophic Lateral SclerosisIs nitric oxide a key target in the pathogenesis of brain lesions during the development of Alzheimer's disease?The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease.SOD1 aggregation in ALS mice shows simplistic test tube behavior.Diffusion of peroxynitrite across erythrocyte membranes.Thermodynamics of protein destabilization in live cellsNuclear localization of human SOD1 and mutant SOD1-specific disruption of survival motor neuron protein complex in transgenic amyotrophic lateral sclerosis mice
P2860
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P2860
description
article publié dans la revue scientifique Nature
@fr
scientific article published in Nature
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в Nature в серпні 1993
@uk
name
ALS, SOD and peroxynitrite
@en
ALS, SOD and peroxynitrite
@nl
type
label
ALS, SOD and peroxynitrite
@en
ALS, SOD and peroxynitrite
@nl
prefLabel
ALS, SOD and peroxynitrite
@en
ALS, SOD and peroxynitrite
@nl
P2093
P356
P1433
P1476
ALS, SOD and peroxynitrite
@en
P2093
P2888
P356
10.1038/364584A0
P407
P577
1993-08-01T00:00:00Z
P6179
1002407083