Insulin rapidly stimulates tyrosine phosphorylation of a Mr-185,000 protein in intact cells
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Interaction of insulin receptor substrate-1 with the sigma3A subunit of the adaptor protein complex-3 in cultured adipocytesDistinct modes of interaction of SHC and insulin receptor substrate-1 with the insulin receptor NPEY region via non-SH2 domainsLocalization of the insulin-like growth factor I receptor binding sites for the SH2 domain proteins p85, Syp, and GTPase activating proteinTyrosine phosphorylation of tub and its association with Src homology 2 domain-containing proteins implicate tub in intracellular signaling by insulin4PS/insulin receptor substrate (IRS)-2 is the alternative substrate of the insulin receptor in IRS-1-deficient miceSimulation predicts IGFBP2-HIF1α interaction drives glioblastoma growthp68 Sam is a substrate of the insulin receptor and associates with the SH2 domains of p85 PI3KSam68 associates with the SH3 domains of Grb2 recruiting GAP to the Grb2-SOS complex in insulin receptor signalingEffect of receptor phosphorylation on the binding between IRS-1 and IGF-1R as revealed by surface plasmon resonance biosensorRecombinant human insulin receptor substrate-1 protein. Tyrosine phosphorylation and in vitro binding of insulin receptor kinaseInvolvement of Src-homology/collagen (SHC) proteins in signaling through the insulin receptor and the insulin-like-growth-factor-I-receptorA brief introduction to FOXOlogyInsulin-like growth factor-I stimulates tyrosine phosphorylation of endogenous c-Crk.Membrane localization of insulin receptor substrate-2 (IRS-2) is associated with decreased overall survival in breast cancerInsulin alters heterogeneous nuclear ribonucleoprotein K protein binding to DNA and RNA.Alzheimer's disease is type 3 diabetes-evidence reviewed.Insulin resistance, obesity, hypertension, and renal sodium transport.The insulin receptor substrate (IRS) proteins: at the intersection of metabolism and cancer.The Rho Guanine Nucleotide Exchange Factor DRhoGEF2 Is a Genetic Modifier of the PI3K Pathway in DrosophilaInsulin receptor substrate-1 prevents autophagy-dependent cell death caused by oxidative stress in mouse NIH/3T3 cells.The heart in obesity-hypertension.Znt7-null mice are more susceptible to diet-induced glucose intolerance and insulin resistance.Novel roles for insulin receptor (IR) in adipocytes and skeletal muscle cells via new and unexpected substrates.Regulating insulin signaling and beta-cell function through IRS proteins.Insulin action 1991.Docking proteins.Clinical science review article: understanding the implications of diabetes on the vascular system.Impact of HCV genetic differences on pathobiology of disease.Antibodies to the insulin receptor as tools in the study of receptor structure and function.The insulin receptor: structure and function.Increased expression of the sterol regulatory element-binding protein-1 gene in insulin receptor substrate-2(-/-) mouse liver.Regulation of the protein kinase activity of the human insulin receptor.Oxygen tension regulates the stability of insulin receptor substrate-1 (IRS-1) through caspase-mediated cleavage.Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells.Insulin receptor substrate-2-dependent interleukin-4 signaling in macrophages is impaired in two models of type 2 diabetes mellitus.Focal adhesion kinase tyrosine phosphorylation is associated with myogenesis and modulated by insulin.Fluorescent indicators for imaging protein phosphorylation in single living cells.Insulin and IGF-I receptor signaling in cultured neurons.Insulin receptor substrate-1 expression is regulated by estrogen in the MCF-7 human breast cancer cell line.p125Fak focal adhesion kinase is a substrate for the insulin and insulin-like growth factor-I tyrosine kinase receptors.
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P2860
Insulin rapidly stimulates tyrosine phosphorylation of a Mr-185,000 protein in intact cells
description
article publié dans la revue scientifique Nature
@fr
scientific article published in Nature
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в Nature в листопаді 1985
@uk
name
Insulin rapidly stimulates tyr ...... 85,000 protein in intact cells
@en
Insulin rapidly stimulates tyr ...... 85,000 protein in intact cells
@nl
type
label
Insulin rapidly stimulates tyr ...... 85,000 protein in intact cells
@en
Insulin rapidly stimulates tyr ...... 85,000 protein in intact cells
@nl
prefLabel
Insulin rapidly stimulates tyr ...... 85,000 protein in intact cells
@en
Insulin rapidly stimulates tyr ...... 85,000 protein in intact cells
@nl
P2093
P356
P1433
P1476
Insulin rapidly stimulates tyr ...... 85,000 protein in intact cells
@en
P2093
P2888
P304
P356
10.1038/318183A0
P407
P577
1985-11-01T00:00:00Z
P6179
1025875577