Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis

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Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis

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im Oktober 2018 veröffentlichter wissenschaftlicher Artikel

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wetenschappelijk artikel

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наукова стаття, опублікована в жовтні 2018

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Ubiquitin ligase RNF8 suppress ...... development and tumorigenesis

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Ubiquitin ligase RNF8 suppress ...... development and tumorigenesis

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Ubiquitin ligase RNF8 suppress ...... development and tumorigenesis

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Ubiquitin ligase RNF8 suppress ...... development and tumorigenesis

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Ubiquitin ligase RNF8 suppress ...... development and tumorigenesis

@en

Ubiquitin ligase RNF8 suppress ...... development and tumorigenesis

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P1476

Ubiquitin ligase RNF8 suppress ...... development and tumorigenesis

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Amine Saad

http://www.w3.org/2001/XMLSchema#string

Anne Hakem

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Brandon Gautreau

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Brian Raught

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Chiara Pastrello

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Deborah Ng

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El Bachir Affar

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Haithem Barbour

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Igor Jurisica

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Kiran Kumar Naidu Guturi

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P2860

WikiPathways: capturing the full diversity of pathway knowledge

RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

Non-canonical ubiquitin-based signals for proteasomal degradation

Mammary stem cells and the differentiation hierarchy: current status and perspectives

From fly wings to targeted cancer therapies: a centennial for notch signaling

Luminal progenitors restrict their lineage potential during mammary gland development

The Sequence Alignment/Map format and SAMtools

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4525-4542

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scholarly article

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10.1172/JCI120401

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English

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128

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2018-10-01T00:00:00Z

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30222135

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6160000

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