about
The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthasesHIV-1 cDNA integration: requirement of HMG I(Y) protein for function of preintegration complexes in vitroIsolation and characterization of novel human immunodeficiency virus integrase inhibitors from fungal metabolitesIsolation and identification of three new 5-alkenyl-3,3(2H)-furanones from two streptomyces species using a genomic screening approach.Benzodiazepine biosynthesis in Streptomyces refuineus.Comparative characterization of the lactimidomycin and iso-migrastatin biosynthetic machineries revealing unusual features for acyltransferase-less type I polyketide synthases and providing an opportunity to engineer new analogues.iso-Migrastatin, migrastatin, and dorrigocin production in Streptomyces platensis NRRL 18993 is governed by a single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase.TLN-05220, TLN-05223, new Echinosporamicin-type antibiotics, and proposed revision of the structure of bravomicins(*).Ligation of highly modified bacteriophage DNA.Biosynthesis of diazepinomicin/ECO-4601, a Micromonospora secondary metabolite with a novel ring system.Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.A genomics-guided approach for discovering and expressing cryptic metabolic pathways.
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description
researcher ORCID ID = 0000-0003-4927-198X
@en
name
Chris M Farnet
@ast
Chris M Farnet
@en
Chris M Farnet
@es
Chris M Farnet
@nl
type
label
Chris M Farnet
@ast
Chris M Farnet
@en
Chris M Farnet
@es
Chris M Farnet
@nl
prefLabel
Chris M Farnet
@ast
Chris M Farnet
@en
Chris M Farnet
@es
Chris M Farnet
@nl
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P108
P1153
6701455849
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P496
0000-0003-4927-198X