The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases
about
Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesisPolyketide synthase chemistry does not direct biosynthetic divergence between 9- and 10-membered enediynesStructural characterization of CalO2: A putative orsellinic acid P450 oxidase in the calicheamicin biosynthetic pathwayStructure and Catalytic Mechanism of the Thioesterase CalE7 in Enediyne BiosynthesisMolecular Basis of Substrate Promiscuity for the SAM-Dependent O -Methyltransferase NcsB1, Involved in the Biosynthesis of the Enediyne Antitumor Antibiotic NeocarzinostatinStructural characterization of CalO1: a putative orsellinic acid methyltransferase in the calicheamicin-biosynthetic pathwayCrystal Structure of the Acyltransferase Domain of the Iterative Polyketide Synthase in Enediyne BiosynthesisEvolutionary implications of bacterial polyketide synthasesAncient horizontal gene transfer from bacteria enhances biosynthetic capabilities of fungiStrain Prioritization and Genome Mining for Enediyne Natural ProductsThe Role of a Nonribosomal Peptide Synthetase in l-Lysine Lactamization During Capuramycin Biosynthesis.Role of sgcR3 in positive regulation of enediyne antibiotic C-1027 production of Streptomyces globisporus C-1027Cyclization of aromatic polyketides from bacteria and fungiCharacterization of the calicheamicin orsellinate C2-O-methyltransferase CalO6.Characterization of the epoxide hydrolase NcsF2 from the neocarzinostatin biosynthetic gene clusterNatural products version 2.0: connecting genes to molecules.Enediyne antitumor antibiotic maduropeptin biosynthesis featuring a C-methyltransferase that acts on a CoA-tethered aromatic substrate.Comparative analysis of the biosynthetic gene clusters and pathways for three structurally related antitumor antibiotics: bleomycin, tallysomycin, and zorbamycin.The biosynthetic genes encoding for the production of the dynemicin enediyne core in Micromonospora chersina ATCC53710Biosynthesis of enediyne antitumor antibioticsEnediyne polyketide synthases stereoselectively reduce the β-ketoacyl intermediates to β-D-hydroxyacyl intermediates in enediyne core biosynthesis.Enediynes: Exploration of microbial genomics to discover new anticancer drug leads.Genome neighborhood network reveals insights into enediyne biosynthesis and facilitates prediction and prioritization for discovery.Enzymatic chemistry of cyclopropane, epoxide, and aziridine biosynthesis.Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027Improvement of secondary metabolite production in Streptomyces by manipulating pathway regulationBiosynthesis and genomic analysis of medium-chain hydrocarbon production by the endophytic fungal isolate Nigrograna mackinnonii E5202H.The biosynthesis, molecular genetics and enzymology of the polyketide-derived metabolites.A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis.Regiospecific O-methylation of naphthoic acids catalyzed by NcsB1, an O-methyltransferase involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatinIncreasing carbohydrate diversity via amine oxidation: aminosugar, hydroxyaminosugar, nitrososugar, and nitrosugar biosynthesis in bacteriaCloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis.Activity screening of carrier domains within nonribosomal peptide synthetases using complex substrate mixtures and large molecule mass spectrometryCharacterization of CalE10, the N-oxidase involved in calicheamicin hydroxyaminosugar formationPredictive model for epoxide hydrolase-generated stereochemistry in the biosynthesis of nine-membered enediyne antitumor antibiotics.Characterization of the SgcF epoxide hydrolase supporting an (R)-vicinal diol intermediate for enediyne antitumor antibiotic C-1027 biosynthesis.Convergent strategies in biosynthesis.The TetR family of regulators.Enhancing the latent nucleotide triphosphate flexibility of the glucose-1-phosphate thymidylyltransferase RmlA.
P2860
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P2860
The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases
description
2005 nî lūn-bûn
@nan
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The neocarzinostatin biosynthe ...... ve type I polyketide synthases
@ast
The neocarzinostatin biosynthe ...... ve type I polyketide synthases
@en
The neocarzinostatin biosynthe ...... ve type I polyketide synthases
@nl
type
label
The neocarzinostatin biosynthe ...... ve type I polyketide synthases
@ast
The neocarzinostatin biosynthe ...... ve type I polyketide synthases
@en
The neocarzinostatin biosynthe ...... ve type I polyketide synthases
@nl
prefLabel
The neocarzinostatin biosynthe ...... ve type I polyketide synthases
@ast
The neocarzinostatin biosynthe ...... ve type I polyketide synthases
@en
The neocarzinostatin biosynthe ...... ve type I polyketide synthases
@nl
P2093
P3181
P1476
The neocarzinostatin biosynthe ...... ve type I polyketide synthases
@en
P2093
Catherine F Yang
Emmanuel Zazopoulos
Jian Zhang
Koichi Nonaka
Liping Nie
Steven D Christenson
Steven G Van Lanen
P304
P3181
P356
10.1016/J.CHEMBIOL.2004.12.013
P407
P577
2005-03-01T00:00:00Z