about
The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis.Downregulation of Rv0189c, encoding a dihydroxyacid dehydratase, affects growth of Mycobacterium tuberculosis in vitro and in miceBiochemical and transcription analysis of acetohydroxyacid synthase isoforms in Mycobacterium tuberculosis identifies these enzymes as potential targets for drug developmentIdentification and validation of novel drug targets in Mycobacterium tuberculosis.Genome-Wide Transposon Mutagenesis in Mycobacterium tuberculosis and Mycobacterium smegmatis.Predictive modeling targets thymidylate synthase ThyX in Mycobacterium tuberculosisIdentification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria.N-Acetylglucosamine-1-phosphate transferase, WecA, as a validated drug target in Mycobacterium tuberculosis.Deoxysugars as antituberculars and alpha-mannosidase inhibitorsThe complex mechanism of antimycobacterial action of 5-fluorouracil.Expanding benzoxazole based inosine 5'-monophosphate dehydrogenase (IMPDH) inhibitor structure-activity as potential anti-tuberculosis agents.Hit discovery of Mycobacterium tuberculosis inosine 5'-monophosphate dehydrogenase, GuaB2, inhibitors.Fragment-Based Approach to Targeting Inosine-5'-monophosphate Dehydrogenase (IMPDH) from Mycobacterium tuberculosis.Detection of Mycobacterium tuberculosis bacilli in bio-aerosols from untreated TB patients3D-QSAR and molecular modeling studies on 2,3-dideoxy hexenopyranosid-4-uloses as anti-tubercular agents targeting alpha-mannosidaseThe quest for the holy grail: new antitubercular chemical entities, targets and strategiesDrug-resistance in Mycobacterium tuberculosis: where we standSynthesis and Structure-Activity relationship of 1-(5-isoquinolinesulfonyl)piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDHSynergistic enhancement of beta-lactam antibiotics by modified tunicamycin analogs TunR1 and TunR2
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description
onderzoeker
@nl
researcher ORCID ID = 0000-0001-9002-2489
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name
Vinayak Singh
@ast
Vinayak Singh
@en
Vinayak Singh
@es
Vinayak Singh
@nl
type
label
Vinayak Singh
@ast
Vinayak Singh
@en
Vinayak Singh
@es
Vinayak Singh
@nl
prefLabel
Vinayak Singh
@ast
Vinayak Singh
@en
Vinayak Singh
@es
Vinayak Singh
@nl
P106
P1153
56177124100
P31
P496
0000-0001-9002-2489