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Targeted ablation of oligodendrocytes triggers axonal damageRecurrent multiple CNS hemangioblastomas with VHL disease treated with pazopanib: a case report and literature review.Infection of type I interferon receptor-deficient mice with various old world arenaviruses: a model for studying virulence and host species barriers.Clival chordoma: a single-centre outcome analysis.T cell-dependence of Lassa fever pathogenesis.IkappaB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappaB in the central nervous systemImmunological mechanism of action and clinical profile of disease-modifying treatments in multiple sclerosis.Replicating viral vector platform exploits alarmin signals for potent CD8+ T cell-mediated tumour immunotherapy.Reconstruction of single cortical projection neurons reveals primary spine loss in multiple sclerosis.USP18 lack in microglia causes destructive interferonopathy of the mouse brain.Myelin membrane wrapping of CNS axons by PI(3,4,5)P3-dependent polarized growth at the inner tongueBrain-resident memory T cells represent an autonomous cytotoxic barrier to viral infectionIn vivo imaging reveals rapid astrocyte depletion and axon damage in a model of neuromyelitis optica-related pathology.B cell-derived transforming growth factor-β1 expression limits the induction phase of autoimmune neuroinflammation.TGFβ regulates persistent neuroinflammation by controlling Th1 polarization and ROS production via monocyte-derived dendritic cells.pMHC affinity controls duration of CD8+ T cell-DC interactions and imprints timing of effector differentiation versus expansion.Interferon-driven deletion of antiviral B cells at the onset of chronic infection.Myelinosome formation represents an early stage of oligodendrocyte damage in multiple sclerosis and its animal model.Interferon-γ-Driven iNOS: A Molecular Pathway to Terminal Shock in Arenavirus Hemorrhagic Fever.Macroautophagy Proteins Control MHC Class I Levels on Dendritic Cells and Shape Anti-viral CD8(+) T Cell Responses.Increased interleukin-27 cytokine expression in the central nervous system of multiple sclerosis patientsOxysterols regulate encephalitogenic CD4(+) T cell trafficking during central nervous system autoimmunity.Aggravation of viral hepatitis by platelet-derived serotonin.Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions.The Immune System Bridges the Gut Microbiota with Systemic Energy Homeostasis: Focus on TLRs, Mucosal Barrier, and SCFAs.STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells.Germline PMS2 and somatic POLE exonuclease mutations cause hypermutability of the leading DNA strand in biallelic mismatch repair deficiency syndrome brain tumours.Toll-like receptor activation reveals developmental reorganization and unmasks responder subsets of microglia.Late motor decline after accomplished remyelination: impact for progressive multiple sclerosis.High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease.Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner.Expression of the DNA-Binding Factor TOX Promotes the Encephalitogenic Potential of Microbe-Induced Autoreactive CD8+ T Cells.Concurrent IDH1 and SMARCB1 Mutations in Pediatric Medulloblastoma: A Case Report.Distinct and Nonredundant In Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous SystemNeurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic StrippingMyeloid-derived suppressor cells control B cell accumulation in the central nervous system during autoimmunityResident-Memory T Cells in Tissue-Restricted Immune Responses: For Better or Worse?The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8 T cellsFunctional Gut Microbiota Remodeling Contributes to the Caloric Restriction-Induced Metabolic ImprovementsHepatocyte growth factor limits autoimmune neuroinflammation via glucocorticoid-induced leucine zipper expression in dendritic cells
P50
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P50
description
researcher ORCID ID = 0000-0002-0247-2007
@en
wetenschapper
@nl
name
Doron Merkler
@ast
Doron Merkler
@en
Doron Merkler
@es
Doron Merkler
@nl
type
label
Doron Merkler
@ast
Doron Merkler
@en
Doron Merkler
@es
Doron Merkler
@nl
prefLabel
Doron Merkler
@ast
Doron Merkler
@en
Doron Merkler
@es
Doron Merkler
@nl
P1053
N-9157-2016
P106
P31
P496
0000-0002-0247-2007