about
Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinaseStructural basis for the recruitment of glycogen synthase by glycogeninMechanism of action of compound-13: an α1-selective small molecule activator of AMPKExpression and purification of functional human glycogen synthase-1:glycogenin-1 complex in insect cells.LKB1 regulates lipid oxidation during exercise independently of AMPKGlucose-6-phosphate-mediated activation of liver glycogen synthase plays a key role in hepatic glycogen synthesis.Mutation in the γ2-subunit of AMP-activated protein kinase stimulates cardiomyocyte proliferation and hypertrophy independent of glycogen storage.Protein kinase C-mediated phosphorylation and activation of PDE3A regulate cAMP levels in human platelets.Dual regulation of glycogen synthase kinase 3 (GSK3)α/β by protein kinase C (PKC)α and Akt promotes thrombin-mediated integrin αIIbβ3 activation and granule secretion in platelets.Protein kinase C and P2Y12 take center stage in thrombin-mediated activation of mammalian target of rapamycin complex 1 in human platelets.Molecular mechanism by which AMP-activated protein kinase activation promotes glycogen accumulation in muscle.mTORC2 protein-mediated protein kinase B (Akt) serine 473 phosphorylation is not required for Akt1 activity in human platelets.The Ca(2+) /calmodulin-dependent kinase kinase β-AMP-activated protein kinase-α1 pathway regulates phosphorylation of cytoskeletal targets in thrombin-stimulated human platelets.Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphataseThe PKB inhibitor Akti-1/2 potentiates PAR-1-mediated platelet function independently of its ability to block PKBDysfunction of the PI3 kinase/Rap1/integrin α(IIb)β(3) pathway underlies ex vivo platelet hypoactivity in essential thrombocythemia
P50
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P50
description
researcher ORCID ID = 0000-0003-0177-1512
@en
wetenschapper
@nl
name
Roger W Hunter
@ast
Roger W Hunter
@en
Roger W Hunter
@nl
type
label
Roger W Hunter
@ast
Roger W Hunter
@en
Roger W Hunter
@nl
prefLabel
Roger W Hunter
@ast
Roger W Hunter
@en
Roger W Hunter
@nl
P31
P496
0000-0003-0177-1512