about
Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genesChromatin signatures of pluripotent cell linesPolycomblike 2 facilitates the recruitment of PRC2 Polycomb group complexes to the inactive X chromosome and to target loci in embryonic stem cells.Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators.XACT Noncoding RNA Competes with XIST in the Control of X Chromosome Activity during Human Early Development.Enlightening the contribution of the dark matter to the X chromosome inactivation process in mammals.Heterochromatin reorganization during early mouse development requires a single-stranded noncoding transcript.Parallel derivation of isogenic human primed and naive induced pluripotent stem cells.A strand-specific burst in transcription of pericentric satellites is required for chromocenter formation and early mouse development.Stem cells primed for action: polycomb repressive complexes restrain the expression of lineage-specific regulators in embryonic stem cells.Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cellsA primate-specific retroviral enhancer wires the XACT lncRNA into the core pluripotency network in humans
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description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Miguel Casanova
@ast
Miguel Casanova
@en
Miguel Casanova
@es
Miguel Casanova
@nl
type
label
Miguel Casanova
@ast
Miguel Casanova
@en
Miguel Casanova
@es
Miguel Casanova
@nl
prefLabel
Miguel Casanova
@ast
Miguel Casanova
@en
Miguel Casanova
@es
Miguel Casanova
@nl
P106
P108
P21
P31
P496
0000-0001-8622-6550