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Cortical overexpression of neuronal calcium sensor-1 induces functional plasticity in spinal cord following unilateral pyramidal tract injury in ratImpaired telomerase activity in human cells expressing GFP-Ku86 fusion proteinsLong-term episomal transgene expression from mitotically stable integration-deficient lentiviral vectors.Chromosomal context and epigenetic mechanisms control the efficacy of genome editing by rare-cutting designer endonucleases.Decay in survival motor neuron and plastin 3 levels during differentiation of iPSC-derived human motor neurons.Efficient Expression of Igf-1 from Lentiviral Vectors Protects In Vitro but Does Not Mediate Behavioral Recovery of a Parkinsonian Lesion in Rats.AMP-activated protein kinase (AMPK)-dependent and -independent pathways regulate hypoxic inhibition of transepithelial Na+ transport across human airway epithelial cells.Integration-deficient lentiviral vectors: a slow coming of age.Large-scale chondroitin sulfate proteoglycan digestion with chondroitinase gene therapy leads to reduced pathology and modulates macrophage phenotype following spinal cord contusion injury.Lentiviral vector-mediated RNA silencing in the central nervous system.Lentiviral vectors encoding short hairpin RNAs efficiently transduce and knockdown LINGO-1 but induce an interferon response and cytotoxicity in central nervous system neurones.Current Progress in Therapeutic Gene Editing for Monogenic DiseasesNonintegrating Gene Therapy Vectors.Chimeric Trojan Protein Insertion in Lentiviral Membranes Makes Lentiviruses Susceptible to Neutralization by Anti-Tetanus Serum Antibodies.African swine fever virus protein pE296R is a DNA repair apurinic/apyrimidinic endonuclease required for virus growth in swine macrophages.Therapeutic strategies for spinal muscular atrophy: SMN and beyond.Comparative analysis of lentiviral vectors and modular protein nanovectors for traumatic brain injury gene therapy.A southern blot protocol to detect chimeric nuclease-mediated gene repair.Transgene delivery to endothelial cultures derived from porcine carotid artery ex vivo.Gene correction of a duchenne muscular dystrophy mutation by meganuclease-enhanced exon knock-in.Challenges for gene therapy of CNS disorders and implications for Parkinson's disease therapies.Highly potent delivery method of gp160 envelope vaccine combining lentivirus-like particles and DNA electrotransfer.Intrastriatal Delivery of Integration-Deficient Lentiviral Vectors in a Rat Model of Parkinson's Disease.10 Years of Rare Disease Day.Gene Therapy, more than ever-a new vision for the journal.Compilation of online resources of relevance to 'Spinraza and advanced therapies: a stakeholder special' issue of Gene Therapy.High-efficiency transduction of spinal cord motor neurons by intrauterine delivery of integration-deficient lentiviral vectors.Induction of the cell survival kinase Sgk1: A possible novel mechanism for α-phenyl-N-tert-butyl nitrone in experimental stroke.Molecular Evidence of Genome Editing in a Mouse Model of Immunodeficiency.Rapid high-resolution karyotyping with precise identification of chromosome breakpointsCAR-T in the clinic: drive with care
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description
researcher
@en
wetenschapper
@nl
հետազոտող
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name
Rafael J Yáñez-Muñoz
@ast
Rafael J Yáñez-Muñoz
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Rafael J Yáñez-Muñoz
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Rafael J Yáñez-Muñoz
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type
label
Rafael J Yáñez-Muñoz
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Rafael J Yáñez-Muñoz
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Rafael J Yáñez-Muñoz
@es
Rafael J Yáñez-Muñoz
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prefLabel
Rafael J Yáñez-Muñoz
@ast
Rafael J Yáñez-Muñoz
@en
Rafael J Yáñez-Muñoz
@es
Rafael J Yáñez-Muñoz
@nl
P106
P21
P31
P496
0000-0001-7113-1938