about
Cyanobacterial Metabolite Calothrixins: Recent Advances in Synthesis and Biological EvaluationStructure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase functionAttenuation of nonsense-mediated mRNA decay enhances in vivo nonsense suppressionTethered dimer inhibitors of NAD synthetase: parallel synthesis of an aryl-substituted SAR library.Structure-Based Discovery of Small Molecule Inhibitors of Cariogenic VirulencePreclinical pharmacology of BA-TPQ, a novel synthetic iminoquinone anticancer agent.L-2-Hydroxyglutarate: an epigenetic modifier and putative oncometabolite in renal cancer.Elevated levels of NO are localized to distal airways in asthmaA facile synthesis of bispyrroloquinone and bispyrroloiminoquinone ring system of marine alkaloidsAntibacterial and Antibiofilm Activities of Makaluvamine AnalogsA novel class of mitochondria-targeted soft electrophiles modifies mitochondrial proteins and inhibits mitochondrial metabolism in breast cancer cells through redox mechanisms.New small-molecule inhibitors of dihydrofolate reductase inhibit Streptococcus mutans.Honokiol inhibits the growth of head and neck squamous cell carcinoma by targeting epidermal growth factor receptorChannel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop.Mitochondrial thiol modification by a targeted electrophile inhibits metabolism in breast adenocarcinoma cells by inhibiting enzyme activity and protein levels.A novel synthetic iminoquinone, BA-TPQ, as an anti-breast cancer agent: in vitro and in vivo activity and mechanisms of action.In vitro and in vivo anticancer activity of novel synthetic makaluvamine analogues.Mini-review: bmx kinase inhibitors for cancer therapy.Identification of the ZAK-MKK4-JNK-TGFβ signaling pathway as a molecular target for novel synthetic iminoquinone anticancer compound BA-TPQ.Synthesis and in vitro anti-lung cancer activity of novel 1, 3, 4, 8-tetrahydropyrrolo [4, 3, 2-de]quinolin-8(1H)-one alkaloid analogs.FBA-TPQ, a novel marine-derived compound as experimental therapy for prostate cancer.Analogs of the marine alkaloid makaluvamines: synthesis, topoisomerase II inhibition, and anticancer activity.Hydroxychalcone inhibitors of Streptococcus mutans glucosyl transferases and biofilms as potential anticaries agents.Synthesis and structure activity relationship studies of novel Staphylococcus aureus Sortase A inhibitors.Synthesis of biotin-tagged chemical cross-linkers and their applications for mass spectrometry.Total Synthesis of Calothrixins A and B via Oxidative Radical Reaction of Cyclohexenone with Aminophenanthridinedione.Pyrrolidinobenzoic acid inhibitors of influenza virus neuraminidase: modifications of essential pyrrolidinone ring substituents.Highly efficient delivery of potent anticancer iminoquinone derivative by multilayer hydrogel cubes.Discovery and evaluation of nNav1.5 sodium channel blockers with potent cell invasion inhibitory activity in breast cancer cells.Tethered dimers as NAD synthetase inhibitors with antibacterial activity.Conjugate addition reactions of alpha-aminoalkylcuprates with alpha, beta-alkenyl-, alpha,beta-alkynyl-, alpha,beta-beta,gamma-allenyl-, and alpha,beta-gamma,delta-dienyl carboxylic acid derivatives, nitriles, and sulfoxidesAn Expedient Synthesis of Murrayaquinone A via a Novel Oxidative Free Radical ReactionInhibition of Streptococcus mutans Biofilms by the Natural Stilbene Piceatannol Through the Inhibition of GlucosyltransferasesBiochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal CancerDiscovery and Characterization of Dual Inhibitors of MDM2 and NFAT1 for Pancreatic Cancer TherapyA Novel Marine Natural Product Derived Pyrroloiminoquinone with Potent Activity against Skin Cancer CellsMDM2-NFAT1 dual inhibitor, MA242: Effective against hepatocellular carcinoma, independent of p53
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description
Forscher
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investigador
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researcher
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ricercatore
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wetenschapper
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հետազոտող
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研究者
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name
Sadanandan E Velu
@ast
Sadanandan E Velu
@en
Sadanandan E Velu
@es
Sadanandan E Velu
@nl
type
label
Sadanandan E Velu
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Sadanandan E Velu
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Sadanandan E Velu
@es
Sadanandan E Velu
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prefLabel
Sadanandan E Velu
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Sadanandan E Velu
@en
Sadanandan E Velu
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Sadanandan E Velu
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P108
P106
P31
P496
0000-0002-0342-2378