In vitro and in vivo anticancer activity of novel synthetic makaluvamine analogues.
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JKA97, a novel benzylidene analog of harmine, exerts anti-cancer effects by inducing G1 arrest, apoptosis, and p53-independent up-regulation of p21Another Look at Pyrroloiminoquinone Alkaloids-Perspectives on Their Therapeutic Potential from Known Structures and Semisynthetic AnaloguesSelective cytotoxicity, inhibition of cell cycle progression, and induction of apoptosis in human breast cancer cells by sesquiterpenoids from Inula lineariifolia Turcz.Experimental therapy of ovarian cancer with synthetic makaluvamine analog: in vitro and in vivo anticancer activity and molecular mechanisms of action.Identification of a new class of MDM2 inhibitor that inhibits growth of orthotopic pancreatic tumors in mice.A quantitative LC-MS/MS method for determination of SP-141, a novel pyrido[b]indole anticancer agent, and its application to a mouse PK study.Natural product ginsenoside 25-OCH3-PPD inhibits breast cancer growth and metastasis through down-regulating MDM2.RYBP expression is associated with better survival of patients with hepatocellular carcinoma (HCC) and responsiveness to chemotherapy of HCC cells in vitro and in vivo.Development and validation of a rapid HPLC method for quantitation of SP-141, a novel pyrido[b]indole anticancer agent, and an initial pharmacokinetic study in mice.Identification of a new class of natural product MDM2 inhibitor: In vitro and in vivo anti-breast cancer activities and target validation.Preclinical evaluation of anticancer efficacy and pharmacological properties of FBA-TPQ, a novel synthetic makaluvamine analog.RYBP predicts survival of patients with non-small cell lung cancer and regulates tumor cell growth and the response to chemotherapy.Inhibiting NFAT1 for breast cancer therapy: New insights into the mechanism of action of MDM2 inhibitor JapATotal synthesis of zyzzyanones A-DIdentification of lineariifolianoid A as a novel dual NFAT1 and MDM2 inhibitor for human cancer therapyA survey of marine natural compounds and their derivatives with anti-cancer activity reported in 2011.Anticancer properties of lamellarins.Antitumor Effect of the Mannich Base(1,3-bis-((3-Hydroxynaphthalen-2-yl)phenylmethyl)urea) on Hepatocellular Carcinoma.Total Synthesis of Calothrixins A and B via Oxidative Radical Reaction of Cyclohexenone with Aminophenanthridinedione.Highly efficient delivery of potent anticancer iminoquinone derivative by multilayer hydrogel cubes.Natural products targeting the p53-MDM2 pathway and mutant p53: Recent advances and implications in cancer medicine
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P2860
In vitro and in vivo anticancer activity of novel synthetic makaluvamine analogues.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
In vitro and in vivo anticancer activity of novel synthetic makaluvamine analogues.
@en
In vitro and in vivo anticancer activity of novel synthetic makaluvamine analogues.
@nl
type
label
In vitro and in vivo anticancer activity of novel synthetic makaluvamine analogues.
@en
In vitro and in vivo anticancer activity of novel synthetic makaluvamine analogues.
@nl
prefLabel
In vitro and in vivo anticancer activity of novel synthetic makaluvamine analogues.
@en
In vitro and in vivo anticancer activity of novel synthetic makaluvamine analogues.
@nl
P2093
P2860
P1476
In vitro and in vivo anticancer activity of novel synthetic makaluvamine analogues
@en
P2093
Dwayaja H Nadkarni
Elizabeth R Rayburn
Ruiwen Zhang
Srinivasan Murugesan
P2860
P304
P356
10.1158/1078-0432.CCR-08-2689
P407
P577
2009-05-01T00:00:00Z