about
P688
Optineurin mediates a negative regulation of Rab8 by the GTPase-activating protein TBC1D17Oligomerization of optineurin and its oxidative stress- or E50K mutation-driven covalent cross-linking: possible relationship with glaucoma pathologyOptineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosisOptineurin negatively regulates the induction of IFNbeta in response to RNA virus infectionPhosphorylation of the autophagy receptor optineurin restricts Salmonella growthInteraction of an adenovirus E3 14.7-kilodalton protein with a novel tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domainsA human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactomeHaploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementiaOptineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutationWidespread macromolecular interaction perturbations in human genetic disordersA novel amyotrophic lateral sclerosis mutation in OPTN induces ER stress and Golgi fragmentation in vitro.Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
P921
Q24294629-530A5D18-4E9E-465C-8A4E-377251E3044CQ24300251-554FAA43-D864-4AE1-888A-E3A52E4F3AC1Q24300284-3383B4BD-54A6-4E7C-AEEF-211E5391A959Q24300481-50F37029-D802-4D5D-917D-14C5FABB9B64Q24304447-F4D49BCA-D641-4164-A695-8C641A1DB9FAQ24314666-94A5EB35-277F-492D-8DCF-1B6C2A4798CCQ24317313-DD607CD8-E58C-4205-913D-69E73F1A52BCQ24323876-87FEA090-1D02-48A8-A507-3A50142A2695Q28118966-4ECBFF7A-CA1D-4387-AB32-BF746A90CDEAQ28771729-03958A44-6172-404C-A5B4-F3A011EBD955Q29347553-4EE15797-7B8D-46AB-909D-967805F6EE1FQ36940515-1A96DE45-C952-4BC6-B09C-45F16C5C8F0B
P921
description
humanes Protein
@de
mammalian protein found in Homo sapiens
@en
menselijk eiwit
@nl
protein
@id
protein
@sv
proteinë
@sq
protèin
@ace
protéine humaine
@fr
بروتين بشري
@ar
name
Optineurin
@en
Optineurin
@nl
type
label
Optineurin
@en
Optineurin
@nl
altLabel
E3-14.7K-interacting protein
@en
FIP-2
@en
HIP-7
@en
Huntingtin interacting protein L
@en
OPTN
@en
TFIIIA-IntP
@en
huntingtin yeast partner L
@en
huntingtin-interacting protein 7
@en
huntingtin-interacting protein L
@en
nemo-related protein
@en
prefLabel
Optineurin
@en
Optineurin
@nl
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NP_001008212
NP_001008213
NP_001008214
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ENSP00000263036
ENSP00000368021
ENSP00000368022
ENSP00000368027
ENSP00000368032
ENSP00000368040
ENSP00000400356
ENSP00000414747
ENSP00000481473
ENSP00000484961