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MUGEN mouse database; animal models of human immunological diseasesA splicing mutation in the novel mitochondrial protein DNAJC11 causes motor neuron pathology associated with cristae disorganization, and lymphoid abnormalities in miceCheminformatics-aided discovery of small-molecule Protein-Protein Interaction (PPI) dual inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL).Solvent Selection for Insoluble Ligands, a Challenge for Biological Assay Development: A TNF-α/SPD304 StudyExclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice.2,2'-Dihydroxybenzophenones and their carbonyl N-analogues as inhibitor scaffolds for MDR-involved human glutathione transferase isoenzyme A1-1.Novel insights into SLC25A46-related pathologies in a genetic mouse modelSimultaneous inhibition of JAK and SYK kinases ameliorates chronic and destructive arthritis in mice.A critical role of the p75 tumor necrosis factor receptor (p75TNF-R) in organ inflammation independent of TNF, lymphotoxin alpha, or the p55TNF-R.The unbearable lightness of bone marrow homeostasis.Rationally designed less toxic SPD-304 analogs and preliminary evaluation of their TNF inhibitory effects.Dissection of the pathologies induced by transmembrane and wild-type tumor necrosis factor in transgenic mice.Tumour necrosis factors in immune regulation: everything that's interesting is...new!Designer xanthone: an inhibitor scaffold for MDR-involved human glutathione transferase isoenzyme A1-1.A RANKL G278R mutation causing osteopetrosis identifies a functional amino acid essential for trimer assembly in RANKL and TNFIn vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitisNew Insights for RANKL as a Proinflammatory Modulator in Modeled Inflammatory ArthritisTumor necrosis factor-receptor 2 is up-regulated on lamina propria T cells in Crohn's disease and promotes experimental colitis in vivoFELASA guidelines for the refinement of methods for genotyping genetically-modified rodents: a report of the Federation of European Laboratory Animal Science Associations Working GroupNovel genetic models of osteoporosis by overexpression of human RANKL in transgenic miceTransgenic Mice Carrying GLUD2 as a Tool for Studying the Expressional and the Functional Adaptation of this Positive Selected Gene in Human Brain EvolutionCurrent Status and Future Prospects of Small-molecule Protein-protein Interaction (PPI) Inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL)Mapping Interactome Networks of DNAJC11, a Novel Mitochondrial Protein Causing Neuromuscular Pathology in MiceIn Silico Discovery of Plant-Origin Natural Product Inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL)Irisin: good or bad for the bone? A new path forward after the reported discovery of irisin receptor?RANKL inhibition improves muscle strength and insulin sensitivity and restores bone mass
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