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FVII, FVIIa, and downstream markers of extrinsic pathway activation differ by EPCR Ser219Gly variant in healthy menAPOE/C1/C4/C2 gene cluster genotypes, haplotypes and lipid levels in prospective coronary heart disease risk among UK healthy menSelection on alleles affecting human longevity and late-life disease: the example of apolipoprotein E.APOE, CETP and LPL genes show strong association with lipid levels in Greek childrenApplication of statistical and functional methodologies for the investigation of genetic determinants of coronary heart disease biomarkers: lipoprotein lipase genotype and plasma triglycerides as an exemplar.A genetic instrument for Mendelian randomization of fibrinogen.Progress in genetic association studies of plasma lipids.Haplotype and genotype effects of the F7 gene on circulating factor VII, coagulation activation markers and incident coronary heart disease in UK men.Networks in Coronary Heart Disease Genetics As a Step towards Systems EpidemiologyClinical Utility of a Coronary Heart Disease Risk Prediction Gene Score in UK Healthy Middle Aged Men and in the Pakistani Population.Genetic meta-analysis of 15,901 African Americans identifies variation in EXOC3L1 is associated with HDL concentration.IRS1 gene variants, dysglycaemic metabolic changes and type-2 diabetes risk.Candidate gene association studies in abdominal aortic aneurysm disease: a review and meta-analysis.Replication and Characterization of Association between ABO SNPs and Red Blood Cell Traits by Meta-Analysis in Europeans.How close are we to implementing a genetic risk score for coronary heart disease?Post-GWAS methodologies for localisation of functional non-coding variants: ANGPTL3.Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.Mechanistic insights from combining genomics with metabolomics.Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis.A genetic risk score is associated with statin-induced low-density lipoprotein cholesterol loweringGene-targeted analysis of copy number variants identifies 3 novel associations with coronary heart disease traits.New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals.Assessment of the clinical utility of adding common single nucleotide polymorphism genetic scores to classical risk factor algorithms in coronary heart disease risk prediction in UK men.Angiotensin-converting enzyme genotype and successful ascent to extreme high altitudeThe use of Meta-Analysis Risk Estimates for Candidate Genes in Combination to Predict Coronary Heart Disease RiskTagging SNP haplotype analysis of the secretory PLA2-V gene, PLA2G5 , shows strong association with LDL and oxLDL levels, suggesting functional distinction from sPLA2-IIA: results from the UDACS studyTrade-off mediated effects on the genetics of human survival caused by increasingly benign living conditionsThe use of genetic information in the prediction of Type 2 diabetesA metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals
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description
investigador
@es
researcher
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name
Fotios Drenos
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Fotios Drenos
@nl
type
label
Fotios Drenos
@en
Fotios Drenos
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Fotios Drenos
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Fotios Drenos
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P31
P496
0000-0003-2469-5516