about
6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinasesRegulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases in cancer.6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase-3 is required for transforming growth factor β1-enhanced invasion of Panc1 cells in vitro.Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth.Fructose-2,6-bisphosphate links glucose to survival and growth.Targeted disruption of inducible 6-phosphofructo-2-kinase results in embryonic lethality.PFKFB2 regulates glycolysis and proliferation in pancreatic cancer cells
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description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Abdullah Yalcin
@en
Abdullah Yalcin
@nl
type
label
Abdullah Yalcin
@en
Abdullah Yalcin
@nl
prefLabel
Abdullah Yalcin
@en
Abdullah Yalcin
@nl
P31
P496
0000-0001-8519-8375