about
Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritisThe inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerizationNLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancerRole of the nlrp3 inflammasome in microbial infection.Fungal chitin dampens inflammation through IL-10 induction mediated by NOD2 and TLR9 activation.The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection.NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cellsToll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-β (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasome-mediated host defense against enteropathogensMurine Borrelia arthritis is highly dependent on ASC and caspase-1, but independent of NLRP3.The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis.Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection.Critical role of caspase-8-mediated IL-1 signaling in promoting Th2 responses during asthma pathogenesis.Role of type I interferons in inflammasome activation, cell death, and disease during microbial infection.FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes.The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis.Addendum: defective Dock2 expression in a subset of ASC-deficient mouse lines.ZBP1/DAI ubiquitination and sensing of influenza vRNPs activate programmed cell death.IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.NLRC3 regulates cellular proliferation and apoptosis to attenuate the development of colorectal cancer.Food for Training-Western Diet and Inflammatory Memory.TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation.Autophagy is redundant for the host defense against systemic Candida albicans infections.Genetic deficiency of NOD2 confers resistance to invasive aspergillosis.Detrimental Type I Interferon Signaling Dominates Protective AIM2 Inflammasome Responses during Francisella novicida InfectionIRF8 Regulates Transcription of Naips for NLRC4 Inflammasome ActivationThe TWIK2 Potassium Efflux Channel in Macrophages Mediates NLRP3 Inflammasome-Induced InflammationFungal ligands released by innate immune effectors promote inflammasome activation during Aspergillus fumigatus infectionGSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever.DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasomeSYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon CancerZBP1 and TAK1: Master Regulators of NLRP3 Inflammasome/Pyroptosis, Apoptosis, and Necroptosis (PAN-optosis)Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity-independent pyroptosis, apoptosis, necroptosis, and inflammatory disease
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description
investigador
@es
researcher
@en
wetenschapper
@nl
name
R K Subbarao Malireddi
@en
R K Subbarao Malireddi
@nl
type
label
R K Subbarao Malireddi
@en
R K Subbarao Malireddi
@nl
prefLabel
R K Subbarao Malireddi
@en
R K Subbarao Malireddi
@nl
P31
P496
0000-0001-8855-9447