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Phagosomal Acidification Prevents Macrophage Inflammatory Cytokine Production to Malaria, and Dendritic Cells Are the Major Source at the Early Stages of Infection: IMPLICATION FOR MALARIA PROTECTIVE IMMUNITY DEVELOPMENTFacile synthesis of antimalarial 1,2-disubstituted 4-quinolones from 1,3-bisaryl-monothio-1,3-diketones.Small molecule-based inhibition of MEK1/2 proteins dampens inflammatory responses to malaria, reduces parasite load, and mitigates pathogenic outcomes.CD36 receptor regulates malaria-induced immune responses primarily at early blood stage infection contributing to parasitemia control and resistance to mortality.Chondroitin sulfate and heparan sulfate proteoglycans of PC12 pheochromocytoma cellsReply
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description
investigador
@es
researcher
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wetenschapper
@nl
name
D Channe Gowda
@en
D Channe Gowda
@nl
type
label
D Channe Gowda
@en
D Channe Gowda
@nl
prefLabel
D Channe Gowda
@en
D Channe Gowda
@nl
P31
P496
0000-0002-6860-5108