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Q27319458-372811A1-7B39-4048-B1BB-618B4FEE9052
Q27319458-372811A1-7B39-4048-B1BB-618B4FEE9052
BestRank
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http://www.wikidata.org/entity/statement/Q27319458-372811A1-7B39-4048-B1BB-618B4FEE9052
The anti-diabetic drug metformin reduces BACE1 protein level by interfering with the MID1 complex
P2860
Q27319458-372811A1-7B39-4048-B1BB-618B4FEE9052
BestRank
Statement
http://www.wikidata.org/entity/statement/Q27319458-372811A1-7B39-4048-B1BB-618B4FEE9052
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wasDerivedFrom
4847acf990e4fe2c6fbdff8dd5eab97b67af7a43
P2860
Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.