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Q34279676-26BCA70B-D4F4-494C-A2FC-FE9B06FF470A
Q34279676-26BCA70B-D4F4-494C-A2FC-FE9B06FF470A
BestRank
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http://www.wikidata.org/entity/statement/Q34279676-26BCA70B-D4F4-494C-A2FC-FE9B06FF470A
Conformational dynamics of CYP3A4 demonstrate the important role of Arg212 coupled with the opening of ingress, egress and solvent channels to dehydrogenation of 4-hydroxy-tamoxifen.
P2860
Q34279676-26BCA70B-D4F4-494C-A2FC-FE9B06FF470A
BestRank
Statement
http://www.wikidata.org/entity/statement/Q34279676-26BCA70B-D4F4-494C-A2FC-FE9B06FF470A
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wasDerivedFrom
8428f37d420a90a19feab11987dce684ca606e30
P2860
4-Hydroxylated metabolites of the antiestrogens tamoxifen and toremifene are metabolized to unusually stable quinone methides.