Conformational dynamics of CYP3A4 demonstrate the important role of Arg212 coupled with the opening of ingress, egress and solvent channels to dehydrogenation of 4-hydroxy-tamoxifen.

Conformational dynamics of CYP3A4 demonstrate the important role of Arg212 coupled with the opening of ingress, egress and solvent channels to dehydrogenation of 4-hydroxy-tamoxifen.

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http://www.wikidata.org/entity/Q34279676
Understanding the mechanism of cytochrome P450 3A4: recent advances and remaining problemsPotent Mechanism-Based Inactivation of Cytochrome P450 2B4 by 9-Ethynylphenanthrene: Implications for Allosteric Modulation of Cytochrome P450 CatalysisA multiscale approach to modelling drug metabolism by membrane-bound cytochrome P450 enzymesF429 Regulation of Tunnels in Cytochrome P450 2B4: A Top Down Study of Multiple Molecular Dynamics SimulationsCurrent Approaches for Investigating and Predicting Cytochrome P450 3A4-Ligand InteractionsCytochrome P450 structure-function: insights from molecular dynamics simulations.Pi-pi Stacking Mediated Cooperative Mechanism for Human Cytochrome P450 3A4.Effects of Hypericum perforatum hydroalcoholic extract, hypericin, and hyperforin on cytotoxicity and CYP3A4 mRNA expression in hepatic cell lines: a comparative studyStructure and Dynamics of Human Drug-Metabolizing Cytochrome P450 Enzymes
P2860

Conformational dynamics of CYP3A4 demonstrate the important role of Arg212 coupled with the opening of ingress, egress and solvent channels to dehydrogenation of 4-hydroxy-tamoxifen.

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http://www.wikidata.org/entity/Q34279676
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年论文
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name
Conformational dynamics of CYP ...... nation of 4-hydroxy-tamoxifen.
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Conformational dynamics of CYP ...... nation of 4-hydroxy-tamoxifen.
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Conformational dynamics of CYP ...... nation of 4-hydroxy-tamoxifen.
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type
label
Conformational dynamics of CYP ...... nation of 4-hydroxy-tamoxifen.
@ast
Conformational dynamics of CYP ...... nation of 4-hydroxy-tamoxifen.
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Conformational dynamics of CYP ...... nation of 4-hydroxy-tamoxifen.
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prefLabel
Conformational dynamics of CYP ...... nation of 4-hydroxy-tamoxifen.
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Conformational dynamics of CYP ...... nation of 4-hydroxy-tamoxifen.
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Conformational dynamics of CYP ...... nation of 4-hydroxy-tamoxifen.
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Conformational dynamics of CYP ...... nation of 4-hydroxy-tamoxifen.
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10.1016/J.BBAGEN.2012.05.011
P407
P433
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P50
P577
P698
P921
P932