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Q34634205-9BE440D6-60B4-45CD-8179-EF619F039157
Q34634205-9BE440D6-60B4-45CD-8179-EF619F039157
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Statement
http://www.wikidata.org/entity/statement/Q34634205-9BE440D6-60B4-45CD-8179-EF619F039157
Conformational activation of antithrombin by heparin involves an altered exosite interaction with protease.
P2860
Q34634205-9BE440D6-60B4-45CD-8179-EF619F039157
BestRank
Statement
http://www.wikidata.org/entity/statement/Q34634205-9BE440D6-60B4-45CD-8179-EF619F039157
rank
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wasDerivedFrom
07f72d1085eda1602cd32d9d266dd1cd19b94e7a
P2860
The oligosaccharide side chain on Asn-135 of alpha-antithrombin, absent in beta-antithrombin, decreases the heparin affinity of the inhibitor by affecting the heparin-induced conformational change.