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Q34995879-D5801122-DEF2-4F24-ABE6-6E1766DAA7B9
Q34995879-D5801122-DEF2-4F24-ABE6-6E1766DAA7B9
BestRank
Statement
http://www.wikidata.org/entity/statement/Q34995879-D5801122-DEF2-4F24-ABE6-6E1766DAA7B9
RIP140 contributes to foam cell formation and atherosclerosis by regulating cholesterol homeostasis in macrophages.
P2860
Q34995879-D5801122-DEF2-4F24-ABE6-6E1766DAA7B9
BestRank
Statement
http://www.wikidata.org/entity/statement/Q34995879-D5801122-DEF2-4F24-ABE6-6E1766DAA7B9
rank
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type
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Statement
wasDerivedFrom
6288c1322832cb53923b998c183d54b7d16fec7c
P2860
ABCA1-mediated cholesterol efflux is defective in free cholesterol-loaded macrophages. Mechanism involves enhanced ABCA1 degradation in a process requiring full NPC1 activity.