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Q35048469-248B1631-4DBD-46E3-ACFC-B0303375BC67
Q35048469-248B1631-4DBD-46E3-ACFC-B0303375BC67
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http://www.wikidata.org/entity/statement/Q35048469-248B1631-4DBD-46E3-ACFC-B0303375BC67
Inhibition of the PI3K/Akt/GSK3 pathway downstream of BCR/ABL, Jak2-V617F, or FLT3-ITD downregulates DNA damage-induced Chk1 activation as well as G2/M arrest and prominently enhances induction of apoptosis.
P2860
Q35048469-248B1631-4DBD-46E3-ACFC-B0303375BC67
BestRank
Statement
http://www.wikidata.org/entity/statement/Q35048469-248B1631-4DBD-46E3-ACFC-B0303375BC67
rank
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wasDerivedFrom
4ff160888ab15a1f19348a3368d992dcfaf94cb8
P2860
Drugging the PI3 kinome: from chemical tools to drugs in the clinic.