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Q35048469-43A287DE-6271-40D9-B441-E7D1A88F1119
Q35048469-43A287DE-6271-40D9-B441-E7D1A88F1119
BestRank
Statement
http://www.wikidata.org/entity/statement/Q35048469-43A287DE-6271-40D9-B441-E7D1A88F1119
Inhibition of the PI3K/Akt/GSK3 pathway downstream of BCR/ABL, Jak2-V617F, or FLT3-ITD downregulates DNA damage-induced Chk1 activation as well as G2/M arrest and prominently enhances induction of apoptosis.
P2860
Q35048469-43A287DE-6271-40D9-B441-E7D1A88F1119
BestRank
Statement
http://www.wikidata.org/entity/statement/Q35048469-43A287DE-6271-40D9-B441-E7D1A88F1119
rank
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type
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wasDerivedFrom
4ff160888ab15a1f19348a3368d992dcfaf94cb8
P2860
FLT3 as a therapeutic target in AML: still challenging after all these years