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Q35624223-116AD5A7-F0BE-47FA-808B-CA540DFB470F
Q35624223-116AD5A7-F0BE-47FA-808B-CA540DFB470F
BestRank
Statement
http://www.wikidata.org/entity/statement/Q35624223-116AD5A7-F0BE-47FA-808B-CA540DFB470F
Cdk1/cyclin B plays a key role in mitotic arrest-induced apoptosis by phosphorylation of Mcl-1, promoting its degradation and freeing Bak from sequestration.
P2860
Q35624223-116AD5A7-F0BE-47FA-808B-CA540DFB470F
BestRank
Statement
http://www.wikidata.org/entity/statement/Q35624223-116AD5A7-F0BE-47FA-808B-CA540DFB470F
rank
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Statement
wasDerivedFrom
b3fdfaedc36f4bbf48479101674623000277a71e
P2860
Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest.