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Q37393446-5725B391-93FD-4DDD-B58C-ADEEF88AB921
Q37393446-5725B391-93FD-4DDD-B58C-ADEEF88AB921
BestRank
Statement
http://www.wikidata.org/entity/statement/Q37393446-5725B391-93FD-4DDD-B58C-ADEEF88AB921
Dantrolene, a therapeutic agent for malignant hyperthermia, markedly improves the function of failing cardiomyocytes by stabilizing interdomain interactions within the ryanodine receptor.
P2860
Q37393446-5725B391-93FD-4DDD-B58C-ADEEF88AB921
BestRank
Statement
http://www.wikidata.org/entity/statement/Q37393446-5725B391-93FD-4DDD-B58C-ADEEF88AB921
rank
NormalRank
type
BestRank
Statement
wasDerivedFrom
25d04e80795fb72099ee47554284859de76d42b7
P2860
Defective regulation of interdomain interactions within the ryanodine receptor plays a key role in the pathogenesis of heart failure.