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Q38335859-B6835473-47C8-4684-8916-35A4A1927FF5
Q38335859-B6835473-47C8-4684-8916-35A4A1927FF5
BestRank
Statement
http://www.wikidata.org/entity/statement/Q38335859-B6835473-47C8-4684-8916-35A4A1927FF5
Merbarone inhibits the catalytic activity of human topoisomerase IIalpha by blocking DNA cleavage.
P2860
Q38335859-B6835473-47C8-4684-8916-35A4A1927FF5
BestRank
Statement
http://www.wikidata.org/entity/statement/Q38335859-B6835473-47C8-4684-8916-35A4A1927FF5
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wasDerivedFrom
d6bffa225eff5d75327cced717abba8820766bf0
P2860
A yeast type II topoisomerase selected for resistance to quinolones. Mutation of histidine 1012 to tyrosine confers resistance to nonintercalative drugs but hypersensitivity to ellipticine.