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Q38343316-301A3D0B-5454-4114-9565-E7AFB1284CAC
Q38343316-301A3D0B-5454-4114-9565-E7AFB1284CAC
BestRank
Statement
http://www.wikidata.org/entity/statement/Q38343316-301A3D0B-5454-4114-9565-E7AFB1284CAC
A mutation in human topoisomerase II alpha whose expression is lethal in DNA repair-deficient yeast cells.
P2860
Q38343316-301A3D0B-5454-4114-9565-E7AFB1284CAC
BestRank
Statement
http://www.wikidata.org/entity/statement/Q38343316-301A3D0B-5454-4114-9565-E7AFB1284CAC
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wasDerivedFrom
3251bc56bb4e8848b05cce66d3afbcc77ddaffea
P2860
Substitutions of Asn-726 in the active site of yeast DNA topoisomerase I define novel mechanisms of stabilizing the covalent enzyme-DNA intermediate.