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Q38878480-7C78F6F9-9692-472C-BDB5-97F3A86CC67F
Q38878480-7C78F6F9-9692-472C-BDB5-97F3A86CC67F
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Statement
http://www.wikidata.org/entity/statement/Q38878480-7C78F6F9-9692-472C-BDB5-97F3A86CC67F
The newly synthesized 2-arylnaphthyridin-4-one, CSC-3436, induces apoptosis of non-small cell lung cancer cells by inhibiting tubulin dynamics and activating CDK1.
P2860
Q38878480-7C78F6F9-9692-472C-BDB5-97F3A86CC67F
BestRank
Statement
http://www.wikidata.org/entity/statement/Q38878480-7C78F6F9-9692-472C-BDB5-97F3A86CC67F
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wasDerivedFrom
f589f0d39535e46d8e3eac11dc6bd0ecdce68674
P2860
Cdk1/cyclin B plays a key role in mitotic arrest-induced apoptosis by phosphorylation of Mcl-1, promoting its degradation and freeing Bak from sequestration.