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Q38940509-91F29ED1-CCC1-498E-8684-D678AC8A60B4
Q38940509-91F29ED1-CCC1-498E-8684-D678AC8A60B4
BestRank
Statement
http://www.wikidata.org/entity/statement/Q38940509-91F29ED1-CCC1-498E-8684-D678AC8A60B4
The discovery of a highly selective 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one SIRT2 inhibitor that is neuroprotective in an in vitro Parkinson's disease model.
P2860
Q38940509-91F29ED1-CCC1-498E-8684-D678AC8A60B4
BestRank
Statement
http://www.wikidata.org/entity/statement/Q38940509-91F29ED1-CCC1-498E-8684-D678AC8A60B4
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wasDerivedFrom
bfa4c7c004d26e544bed87c048915b5b3fd02e5d
P2860
SIRT2 down-regulation in HeLa can induce p53 accumulation via p38 MAPK activation-dependent p300 decrease, eventually leading to apoptosis.