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1
Q39537237-84845CBF-5CCA-4CB8-B416-625DAF02F2A4
Q39537237-84845CBF-5CCA-4CB8-B416-625DAF02F2A4
BestRank
Statement
http://www.wikidata.org/entity/statement/Q39537237-84845CBF-5CCA-4CB8-B416-625DAF02F2A4
Potent antipneumococcal activity of gemifloxacin is associated with dual targeting of gyrase and topoisomerase IV, an in vivo target preference for gyrase, and enhanced stabilization of cleavable complexes in vitro.
P2860
Q39537237-84845CBF-5CCA-4CB8-B416-625DAF02F2A4
BestRank
Statement
http://www.wikidata.org/entity/statement/Q39537237-84845CBF-5CCA-4CB8-B416-625DAF02F2A4
rank
NormalRank
type
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Statement
wasDerivedFrom
176ec2af389e7490a8f0dd40bcc1993398486221
P2860
Engineering the specificity of antibacterial fluoroquinolones: benzenesulfonamide modifications at C-7 of ciprofloxacin change its primary target in Streptococcus pneumoniae from topoisomerase IV to gyrase.