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Q46890874-2B792C1E-885F-4280-9AED-3CBC5BDAD6F7
Q46890874-2B792C1E-885F-4280-9AED-3CBC5BDAD6F7
BestRank
Statement
http://www.wikidata.org/entity/statement/Q46890874-2B792C1E-885F-4280-9AED-3CBC5BDAD6F7
p21CDKN1A allows the repair of replication-mediated DNA double-strand breaks induced by topoisomerase I and is inactivated by the checkpoint kinase inhibitor 7-hydroxystaurosporine.
P2860
Q46890874-2B792C1E-885F-4280-9AED-3CBC5BDAD6F7
BestRank
Statement
http://www.wikidata.org/entity/statement/Q46890874-2B792C1E-885F-4280-9AED-3CBC5BDAD6F7
rank
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type
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wasDerivedFrom
6ccef7b1658276abcb6345824ee379400b22d572
P2860
Potentiation of cytotoxicity of topoisomerase i poison by concurrent and sequential treatment with the checkpoint inhibitor UCN-01 involves disparate mechanisms resulting in either p53-independent clonogenic suppression or p53-dependent mitotic cata