Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylaseCTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2Imprinting mutation in the Beckwith-Wiedemann syndrome leads to biallelic IGF2 expression through an H19-independent pathwayPlacental overgrowth in mice lacking the imprinted gene IplEvidence that paternal expression of the epsilon-sarcoglycan gene accounts for reduced penetrance in myoclonus-dystoniaThe H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1rA maternally methylated CpG island in KvLQT1 is associated with an antisense paternal transcript and loss of imprinting in Beckwith-Wiedemann syndromeSilencing of CDKN1C (p57KIP2) is associated with hypomethylation at KvDMR1 in Beckwith-Wiedemann syndromeBeckwith-Wiedemann syndrome and assisted reproduction technology (ART)Analysis of germline CDKN1C (p57KIP2) mutations in familial and sporadic Beckwith-Wiedemann syndrome (BWS) provides a novel genotype-phenotype correlationCommon polymorphism in H19 associated with birthweight and cord blood IGF-II levels in humansReprogramming DNA methylation in the mammalian life cycle: building and breaking epigenetic barriersConceptual links between DNA methylation reprogramming in the early embryo and primordial germ cellsEtoposide induces nuclear re-localisation of AIDPairing of homologous regions in the mouse genome is associated with transcription but not imprinting statusSequence conservation and variability of imprinting in the Beckwith-Wiedemann syndrome gene cluster in human and mouseEpigenetic reprogramming in mammalian developmentQuantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolutionActivation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogrammingImprinted genes, placental development and fetal growthA developmental window of opportunity for imprinted gene silencing mediated by DNA methylation and the Kcnq1ot1 noncoding RNAProcessive DNA demethylation via DNA deaminase-induced lesion resolution5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogrammingLoss of the maternal H19 gene induces changes in Igf2 methylation in both cis and transEvolution and functions of long noncoding RNAsStability and flexibility of epigenetic gene regulation in mammalian developmentGenomic imprinting: parental influence on the genomeDynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiationDeepCpG: accurate prediction of single-cell DNA methylation states using deep learningDirect sequencing of small genomes on the Pacific Biosciences RS without library preparationAn upstream repressor element plays a role in Igf2 imprintingCohesin is required for higher-order chromatin conformation at the imprinted IGF2-H19 locus.Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes.Germline mutation in NLRP2 (NALP2) in a familial imprinting disorder (Beckwith-Wiedemann Syndrome).Multi-tissue DNA methylation age predictor in mouse.Raised late pregnancy glucose concentrations in mice carrying pups with targeted disruption of H19delta13A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation.Tracking the embryonic stem cell transition from ground state pluripotency.Age at onset in Huntington's disease and methylation at D4S95Epigenetic modification and uniparental inheritance of H19 in Beckwith-Wiedemann syndrome.
P50
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P50
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Duits onderzoeker
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German scientist
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científico alemán
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investigador alemán
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عالم ألماني
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Wolf Reik
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Wolf Reik
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Wolf Reik
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Wolf Reik
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Wolf Reik
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Wolf Reik
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Wolf Reik
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Wolf Reik
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Wolf Reik
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Reik W
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Reik W.
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Wolf Reik
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Wolf Reik
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Wolf Reik
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Wolf Reik
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Wolf Reik
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Wolf Reik
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Wolf Reik
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2000-01-01T00:00:00Z