Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming
about
AID and APOBECs span the gap between innate and adaptive immunityPrimordial germ cells in miceActivation-induced cytidine deaminase auto-activates and triggers aberrant gene expressionOptimal functional levels of activation-induced deaminase specifically require the Hsp40 DnaJa1Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brainThymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sitesReprogramming towards pluripotency requires AID-dependent DNA demethylationGADD45 proteins: central players in tumorigenesisEpigenetic regulation of neurogenesis in the adult mammalian brainEstablishing, maintaining and modifying DNA methylation patterns in plants and animalsAlternative induction of meiotic recombination from single-base lesions of DNA deaminasesMechanisms and functions of Tet protein-mediated 5-methylcytosine oxidationActive DNA demethylation in post-mitotic neurons: a reason for optimismReprogramming DNA methylation in the mammalian life cycle: building and breaking epigenetic barriersThe epigenetic basis of diffuse large B-cell lymphomaThe roles of retinoic acid and retinoic acid receptors in inducing epigenetic changesA concise review on epigenetic regulation: insight into molecular mechanismsEtoposide induces nuclear re-localisation of AIDExcision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: structural basis and implications for active DNA demethylationExcision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylationEpigenetic modifications: basic mechanisms and role in cardiovascular disease.Inflammation and skeletal metastasisEmbryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stabilitySimultaneous in vitro characterisation of DNA deaminase function and associated DNA repair pathwaysProcessive DNA demethylation via DNA deaminase-induced lesion resolutionReprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosinePlasticity of DNA methylation in mouse T cell activation and differentiationActivation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with ageEpigenetic mechanisms in mammalsMissing heritability and strategies for finding the underlying causes of complex diseaseAID and Apobec3G haphazard deamination and mutational diversityTemporal and epigenetic regulation of neurodevelopmental plasticity.GADD45A does not promote DNA demethylation.Insulin gene expression is regulated by DNA methylationBase excision repair of tandem modifications in a methylated CpG dinucleotide.Active demethylation in mouse zygotes involves cytosine deamination and base excision repairTransgenerational genetic effects of the paternal Y chromosome on daughters' phenotypes.Fine-tuning of iPSC derivation by an inducible reprogramming system at the protein level.APOBEC3B, a molecular driver of mutagenesis in human cancers.Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes
P2860
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P2860
Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Activation-induced cytidine de ...... s for epigenetic reprogramming
@ast
Activation-induced cytidine de ...... s for epigenetic reprogramming
@en
Activation-induced cytidine de ...... s for epigenetic reprogramming
@nl
type
label
Activation-induced cytidine de ...... s for epigenetic reprogramming
@ast
Activation-induced cytidine de ...... s for epigenetic reprogramming
@en
Activation-induced cytidine de ...... s for epigenetic reprogramming
@nl
prefLabel
Activation-induced cytidine de ...... s for epigenetic reprogramming
@ast
Activation-induced cytidine de ...... s for epigenetic reprogramming
@en
Activation-induced cytidine de ...... s for epigenetic reprogramming
@nl
P2093
P2860
P3181
P356
P1476
Activation-induced cytidine de ...... s for epigenetic reprogramming
@en
P2093
Heather A Coker
Hugh D Morgan
Svend K Petersen-Mahrt
P2860
P304
52353-52360
P3181
P356
10.1074/JBC.M407695200
P407
P577
2004-09-24T00:00:00Z