Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations
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Common polymorphisms influencing serum uric acid levels contribute to susceptibility to gout, but not to coronary artery diseaseAssociation of rs780094 in GCKR with metabolic traits and incident diabetes and cardiovascular disease: the ARIC StudyA meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americansGWAS of 126,559 individuals identifies genetic variants associated with educational attainmentSex and age interaction with genetic association of atherogenic uric acid concentrationsCommon variants in SLC17A3 gene affect intra-personal variation in serum uric acid levels in longitudinal time seriesCommon variant of leucine-rich repeat-containing 16A (LRRC16A) gene is associated with gout susceptibilityCohort Profile: TwinsUK and healthy ageing twin studyGenome-wide association analyses identify 18 new loci associated with serum urate concentrationsThe genetics of hyperuricaemia and goutPredictive value of 8 genetic loci for serum uric acid concentrationUrate Handling in the Human BodyRenal transport of uric acid: evolving concepts and uncertaintiesGenetics of human metabolism: an updateSLC17: a functionally diverse family of organic anion transportersNatural Products Improving Hyperuricemia with Hepatorenal Dual EffectsThe organic anion transporter (OAT) family: a systems biology perspectiveHuman metabolic individuality in biomedical and pharmaceutical researchGenome-wide association study identifies multiple loci influencing human serum metabolite levelsCommon variants related to serum uric acid concentrations are associated with glucose metabolism and insulin secretion in a Chinese populationExtra-renal elimination of uric acid via intestinal efflux transporter BCRP/ABCG2Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing StudyAllopurinol: insights from studies of dose-response relationships.Association between SLC2A9 (GLUT9) gene polymorphisms and gout susceptibility: an updated meta-analysis.Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.Juvenile cataract-associated mutation of solute carrier SLC16A12 impairs trafficking of the protein to the plasma membrane.The frequency of single nucleotide polymorphisms and their association with uric acid concentration based on data from genome-wide association studies in the Korean population.Detection of pleiotropy through a Phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) study.Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarnitines in Whole Blood.Genome-wide methylation data mirror ancestry information.Homozygous SLC2A9 mutations cause severe renal hypouricemia.Prioritizing GWAS results: A review of statistical methods and recommendations for their application.Ependymal cells of the mouse brain express urate transporter 1 (URAT1)Validation of standard operating procedures in a multicenter retrospective study to identify -omics biomarkers for chronic low back pain.Association of functional polymorphism rs2231142 (Q141K) in the ABCG2 gene with serum uric acid and gout in 4 US populations: the PAGE Study.Management of hyperuricemia in gout: focus on febuxostat.Association of nephrolithiasis and gene for glucose transporter type 9 (SLC2A9): study of 145 patients.Uric acid: the past decadeInteractions between genetic variants in glucose transporter type 9 (SLC2A9) and dietary habits in serum uric acid regulation.Association of a polymorphism in a gene encoding a urate transporter with CKD progression.
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P248
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P2860
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Meta-analysis of 28,141 indivi ...... uence uric acid concentrations
@ast
Meta-analysis of 28,141 indivi ...... uence uric acid concentrations
@en
Meta-analysis of 28,141 indivi ...... uence uric acid concentrations
@en-gb
Meta-analysis of 28,141 indivi ...... uence uric acid concentrations
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type
label
Meta-analysis of 28,141 indivi ...... uence uric acid concentrations
@ast
Meta-analysis of 28,141 indivi ...... uence uric acid concentrations
@en
Meta-analysis of 28,141 indivi ...... uence uric acid concentrations
@en-gb
Meta-analysis of 28,141 indivi ...... uence uric acid concentrations
@nl
altLabel
Meta-Analysis of 28,141 Indivi ...... uence Uric Acid Concentrations
@en
prefLabel
Meta-analysis of 28,141 indivi ...... uence uric acid concentrations
@ast
Meta-analysis of 28,141 indivi ...... uence uric acid concentrations
@en
Meta-analysis of 28,141 indivi ...... uence uric acid concentrations
@en-gb
Meta-analysis of 28,141 indivi ...... uence uric acid concentrations
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P2093
P2860
P50
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P3181
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Meta-analysis of 28,141 indivi ...... uence uric acid concentrations
@en
P2093
Alan F Wright
Angela Doering
Dawn Waterworth
Eva Albrecht
Harry Campbell
John B Whitfield
John Connell
John Peden
Melanie Kolz
Morris Brown
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1000504
P407
P50
P577
2009-06-01T00:00:00Z