Genome-wide association analyses identify 18 new loci associated with serum urate concentrations
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Metabolomics: Bridging the Gap between Pharmaceutical Development and Population HealthUrate Handling in the Human BodyGenetics of human metabolism: an updateLinking uric acid metabolism to diabetic complicationsSLC transporters as therapeutic targets: emerging opportunitiesSLC2A9 Genotype Is Associated with SLC2A9 Gene Expression and Urinary Uric Acid ConcentrationThe anatomical distribution of genetic associations.Review: Gout: A Roadmap to Approaches for Improving Global OutcomesABCG2: the molecular mechanisms of urate secretion and gout12q24 locus association with type 1 diabetes: SH2B3 or ATXN2?Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian womenGenetic variation underlying renal uric acid excretion in Hispanic children: the Viva La Familia StudyQuality control and conduct of genome-wide association meta-analysesGenome-wide association study of chronic periodontitis in a general German populationA genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in JapaneseAllopurinol: insights from studies of dose-response relationships.Mendelian Randomization as an Approach to Assess Causality Using Observational Data.The Sweet Path to Metabolic Demise: Fructose and Lipid SynthesisThe frequency of single nucleotide polymorphisms and their association with uric acid concentration based on data from genome-wide association studies in the Korean population.Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.Detection of pleiotropy through a Phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) study.ABCG2 polymorphisms in gout: insights into disease susceptibility and treatment approachesTT genotype of rs2941484 in the human HNF4G gene is associated with hyperuricemia in Chinese Han men.The genetics of gout: towards personalised medicine?Serum uric acid levels and multiple health outcomes: umbrella review of evidence from observational studies, randomised controlled trials, and Mendelian randomisation studiesReplication of Gout/Urate Concentrations GWAS Susceptibility Loci Associated with Gout in a Han Chinese Population.Impact of comorbidities on gout and hyperuricaemia: an update on prevalence and treatment optionsInteraction of the GCKR and A1CF loci with alcohol consumption to influence the risk of goutCausal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study.Copy number polymorphisms near SLC2A9 are associated with serum uric acid concentrationsPleiotropic genes for metabolic syndrome and inflammationCohort Profile: Estonian Biobank of the Estonian Genome Center, University of Tartu.Abundant local interactions in the 4p16.1 region suggest functional mechanisms underlying SLC2A9 associations with human serum uric acidIdentifying causal variants at loci with multiple signals of associationRenal clearance of uric acid is linked to insulin resistance and lower excretion of sodium in gout patients.Impaired response or insufficient dosage? Examining the potential causes of "inadequate response" to allopurinol in the treatment of goutAn old disease with new insights: Update on diagnosis and treatment of gout.Sugar-sweetened beverage consumption: a risk factor for prevalent gout with SLC2A9 genotype-specific effects on serum urate and risk of gout.Gout: a review of nonmodifiable and modifiable risk factors.Positive association of tomato consumption with serum urate: support for tomato consumption as an anecdotal trigger of gout flares.
P2860
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P2860
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations
description
2013 nî lūn-bûn
@nan
2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
name
Genome-wide association analys ...... ith serum urate concentrations
@ast
Genome-wide association analys ...... ith serum urate concentrations
@en
Genome-wide association analys ...... ith serum urate concentrations
@nl
type
label
Genome-wide association analys ...... ith serum urate concentrations
@ast
Genome-wide association analys ...... ith serum urate concentrations
@en
Genome-wide association analys ...... ith serum urate concentrations
@nl
prefLabel
Genome-wide association analys ...... ith serum urate concentrations
@ast
Genome-wide association analys ...... ith serum urate concentrations
@en
Genome-wide association analys ...... ith serum urate concentrations
@nl
P2093
P2860
P50
P3181
P356
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P1476
Genome-wide association analys ...... ith serum urate concentrations
@en
P2093
Aaron Isaacs
Adrienne Tin
Afshin Parsa
Alan F Wright
Aldi Kraja
Andrew D Johnson
Angelo L Gaffo
Anne Grotevendt
Antonio Lupo
P2860
P2888
P304
P3181
P356
10.1038/NG.2500
P407
P50
P5008
P577
2013-02-01T00:00:00Z
P5875
P6179
1021326074