about
P688
TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancerInhibitor of apoptosis (IAP) proteins in regulation of inflammation and innate immunityTWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8To fight or die - inhibitor of apoptosis proteins at the crossroad of innate immunity and deathCellular inhibitor of apoptosis protein-1 (cIAP1) can regulate E2F1 transcription factor-mediated control of cyclin transcriptionAsymmetric recruitment of cIAPs by TRAF2cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoformsThe structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9IAPs: more than just inhibitors of apoptosis proteinscIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)cIAP1 Localizes to the nuclear compartment and modulates the cell cycleInteraction of heat-shock protein 90 beta isoform (HSP90 beta) with cellular inhibitor of apoptosis 1 (c-IAP1) is required for cell differentiationUbiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuliThe TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteinsSelf-termination of the terminatorThe F-box protein Fbxo7 interacts with human inhibitor of apoptosis protein cIAP1 and promotes cIAP1 ubiquitinationA protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway
P921
Q50260892-626C46C8-F9F1-4D74-9BF4-BAF98AF46444Q50263899-05FA18E3-77E7-4904-92C3-50D870C79F06Q50263907-51BFBE1D-8444-499A-9E9A-65125561C515Q50268948-1AA14858-812B-465F-B1F9-7FF7C81EB3A0Q50270855-8A0F760B-ACAE-4795-950E-16DB40525FFCQ50270872-F54D67D9-16B9-4534-B42C-4DADF8CB24F1Q50297389-65721D30-6EDA-4544-B474-30060481AB06Q50297389-C53349C2-BEAF-4061-AD36-E0826DC01E93
P527
Q24292505-AE660AAE-62F4-497D-BA31-C2B322C53450Q24292870-037830EE-0D2B-4C8F-8D32-3396B78103AFQ24298292-0C6C1D17-DB06-41E5-B8F7-15D12FD62C24Q24300508-263D07F0-2BAB-4104-9B55-7BE7E1DB5F78Q24301502-614AB59C-9DF2-4316-A92C-B6D20C6D7514Q24306110-85763A3B-0608-4621-B757-9BF42A61A8BCQ24310283-94AAA933-7ACE-4449-8AE1-CEDB7E2CA6ADQ24311676-196F13FC-3E49-4552-9A9B-5A24CCD5E219Q24318374-DADA1054-B175-4A1C-AA4C-9322E330EBDEQ24321918-FD5EB78F-DDC0-42E9-9395-77498638CF76Q24338276-F5FE05DB-4FA3-4979-BF7F-A49D75F7F7CFQ24338725-5A614530-ACF8-4E59-8DEB-1AD7C36BD0E5Q28114973-2369E592-BFAD-4773-A278-DB48EFFF5D2DQ28116145-A3BA25EA-B8A9-46C4-B59E-4C2FED9E8DF7Q28117866-20049D6D-FCB1-4041-87DD-B13BCCFE9EA4Q28118772-9D116187-FFFA-444B-823E-29F51FBDE3FDQ28118915-E4F7BB14-F733-4F81-AD1A-42E7777A1ED2Q60044295-92F756AF-5F65-45B5-8ABA-34529E3FAF72
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
proteinë
@sq
proteïne in Baculoviral IAP repeat containing 2
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
Baculoviral IAP repeat containing 2
@en
Baculoviral IAP repeat containing 2
@nl
type
label
Baculoviral IAP repeat containing 2
@en
Baculoviral IAP repeat containing 2
@nl
altLabel
BIRC2
@en
C-IAP1
@en
IAP homolog B
@en
IAP-2
@en
NFR2-TRAF signalling complex protein
@en
RING finger protein 48
@en
RING-type E3 ubiquitin transferase BIRC2
@en
TNFR2-TRAF-signaling complex protein 2
@en
apoptosis inhibitor 1
@en
baculoviral IAP repeat-containing protein 2
@en
prefLabel
Baculoviral IAP repeat containing 2
@en
Baculoviral IAP repeat containing 2
@nl
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P705
P352
P31
P352
P637
NP_001243092
NP_001243095
P638
P680
P681
P682
P702
P703
P705
ENSP00000227758
ENSP00000431723
ENSP00000432410
ENSP00000433851
ENSP00000434557
ENSP00000434708
ENSP00000434979
ENSP00000436741
ENSP00000477613
ENSP00000484838