Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli
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Rotavirus NSP1 inhibits NFkappaB activation by inducing proteasome-dependent degradation of beta-TrCP: a novel mechanism of IFN antagonismSilencing of the XAF1 gene by promoter hypermethylation in cancer cells and reactivation to TRAIL-sensitization by IFN-betaProtective roles of NF-kB for chromium (VI)-induced cytotoxicity is revealed by expression of IkB kinase-B mutantN-Terminally extended human ubiquitin-conjugating enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulumAPC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complexIAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition.Functional activities and cellular localization of the ezrin, radixin, moesin (ERM) and RING zinc finger domains in MIRNotch inhibits apoptosis by direct interference with XIAP ubiquitination and degradationRegulation of the copper chaperone CCS by XIAP-mediated ubiquitinationCartilage oligomeric matrix protein protects cells against death by elevating members of the IAP family of survival proteinscIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomasThe p53-inducible E3 ubiquitin ligase p53RFP induces p53-dependent apoptosisA novel role for XIAP in copper homeostasis through regulation of MURR1VIAF, a conserved inhibitor of apoptosis (IAP)-interacting factor that modulates caspase activationA novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomesThe IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptorNrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosisX-linked inhibitor of apoptosis protein (XIAP) regulates PTEN ubiquitination, content, and compartmentalizationARTS and Siah collaborate in a pathway for XIAP degradationIdentification of ARIA regulating endothelial apoptosis and angiogenesis by modulating proteasomal degradation of cIAP-1 and cIAP-2RNF152, a novel lysosome localized E3 ligase with pro-apoptotic activitiesThe USP19 deubiquitinase regulates the stability of c-IAP1 and c-IAP2Suppression of caspase-8- and -10-associated RING proteins results in sensitization to death ligands and inhibition of tumor cell growthNARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF)Livin promotes Smac/DIABLO degradation by ubiquitin-proteasome pathwayTNF-alpha induced c-IAP1/TRAF2 complex translocation to a Ubc6-containing compartment and TRAF2 ubiquitinationInhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs.Isolation of a murine homologue of the Drosophila neuralized gene, a gene required for axonemal integrity in spermatozoa and terminal maturation of the mammary glandMolecular cloning of ILP-2, a novel member of the inhibitor of apoptosis protein familyUpstream regulatory role for XIAP in receptor-mediated apoptosisIs NF-kappaB a good target for cancer therapy? Hopes and pitfallsHECT and RING finger families of E3 ubiquitin ligases at a glancec-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activationThe mitochondrial ARTS protein promotes apoptosis through targeting XIAPUbiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell deathA death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPKProteolytic cleavage of Livin (ML-IAP) in apoptotic melanoma cells potentially mediated by a non-canonical caspaseOmi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosisThe anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites
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P2860
Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli
description
2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 2000
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scientific journal article
@en
vedecký článok (publikovaný 2000/05/05)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/05/05)
@nl
наукова стаття, опублікована в травні 2000
@uk
مقالة علمية (نشرت في 5-5-2000)
@ar
name
Ubiquitin protein ligase activ ...... response to apoptotic stimuli
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Ubiquitin protein ligase activ ...... response to apoptotic stimuli
@en
Ubiquitin protein ligase activ ...... response to apoptotic stimuli
@nl
type
label
Ubiquitin protein ligase activ ...... response to apoptotic stimuli
@ast
Ubiquitin protein ligase activ ...... response to apoptotic stimuli
@en
Ubiquitin protein ligase activ ...... response to apoptotic stimuli
@nl
prefLabel
Ubiquitin protein ligase activ ...... response to apoptotic stimuli
@ast
Ubiquitin protein ligase activ ...... response to apoptotic stimuli
@en
Ubiquitin protein ligase activ ...... response to apoptotic stimuli
@nl
P2093
P921
P3181
P1433
P1476
Ubiquitin protein ligase activ ...... response to apoptotic stimuli
@en
P2093
A. M. Weissman
J. D. Ashwell
J. P. Jensen
P304
P3181
P356
10.1126/SCIENCE.288.5467.874
P407
P577
2000-05-05T00:00:00Z