about
p-ERBB2 heterodimers:PTK6p-Y342-PTK6:p-Y250-STAP2p-Y342-PTK6:p-Y315;Y326-AKT1HBEGF:EGFR:p-Y525-GPNMB:LINC01139:PTK6:LRRK2Activated ERBB2 binds PTK6 (BRK)HIF1A;EPAS1 promote PTK6 gene expressionPTK6 translocates to the nucleusPhosphorylated GPNMB recruits PTK6 and LRRK2 in the presence of LINC01139PTPN1 dephosphorylates PTK6
P527
P688
Sik (BRK) phosphorylates Sam68 in the nucleus and negatively regulates its RNA binding abilityIdentification of twinfilin-2 as a factor involved in neurite outgrowth by RNAi-based screenSignal transducer and activator of transcription 5b: a new target of breast tumor kinase/protein tyrosine kinase 6Regulation of the nonreceptor tyrosine kinase Brk by autophosphorylation and by autoinhibitionIdentification of STAT3 as a specific substrate of breast tumor kinaseRegulated association of protein kinase B/Akt with breast tumor kinaseCloning and characterisation of cDNAs encoding a novel non-receptor tyrosine kinase, brk, expressed in human breast tumoursBrk activates rac1 and promotes cell migration and invasion by phosphorylating paxillinStructural basis of the auto-inhibition mechanism of nonreceptor tyrosine kinase PTK6Solution structure and backbone dynamics of the non-receptor protein-tyrosine kinase-6 Src homology 2 domainProtein-tyrosine kinase 6 promotes peripheral adhesion complex formation and cell migration by phosphorylating p130 CRK-associated substrateProtein tyrosine kinase 6 directly phosphorylates AKT and promotes AKT activation in response to epidermal growth factorBrk is coamplified with ErbB2 to promote proliferation in breast cancerSTAP-2 is phosphorylated at tyrosine-250 by Brk and modulates Brk-mediated STAT3 activationBrk/Protein tyrosine kinase 6 phosphorylates p27KIP1, regulating the activity of cyclin D-cyclin-dependent kinase 4PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1Breast tumor kinase phosphorylates p190RhoGAP to regulate rho and ras and promote breast carcinoma growth, migration, and invasionThe LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer
P921
Q50271912-659F8EE6-D7DD-41F1-A259-FF314A8AD921Q50274296-1B48A271-E158-4B57-AACA-45C5D66A8E7AQ50274313-3A6866C5-098B-4F8B-9957-85F797E00A1BQ50274319-96CC24F9-1510-4005-B0A9-4F7D267B100DQ50298016-7AB55CE4-D3F2-4FAE-A292-40013C192377Q50299250-BCCD9207-0437-4173-AED9-DAA956A15542Q50299276-8EC36FCC-425D-40F0-9EF3-DF0F737627EBQ50299276-DA283998-D45A-4AD0-9207-0A0D0554569BQ50299295-9A104F34-B8BE-4A90-A613-7B022FE136BAQ50299301-6A25E2D2-EB51-49CD-8FB8-3BDEB6000E0C
P527
Q22254678-1A1E391E-84FA-477E-A64F-89AAF52729C2Q24296143-3A98EA53-91F4-4D36-A86A-32CB93ED3F36Q24300274-40403D95-CAEC-4C11-9EFA-C71CE5444D4AQ24301621-5E77A22E-D945-4CE8-A6C1-465B8E5467C5Q24311267-29A5AE25-586F-491D-A23A-1694871ECEB5Q24314300-40241954-1702-4427-B940-B0B695218E13Q24314895-70ABBE84-1D2D-4FE6-AF08-CBF828C8A5EAQ24318315-5E4DFFB4-1A80-42F0-8542-D6552C000F86Q24319876-37278CA2-DF94-4790-8703-4287A26842FAQ24322847-2C1EBE94-74D6-449D-8AC9-417BCA49B14BQ28115210-EAC32A9F-1575-4630-A01A-594779E2661EQ28115391-F6F415BE-564D-4516-B47B-2CF1C8A51E80Q28115616-C124EA0D-DAD8-498B-ABA1-BA8CE441EFB9Q28115685-2C23E6D3-50EF-4AB8-9C23-D624CDF5D01DQ28115769-FCADBDCD-E178-47F7-94D8-203B80DCA265Q28116075-C399AC7E-2A96-4B86-A810-354B137E9737Q28116255-20DE2794-D37E-4DDE-AF98-AF3BF043E24CQ28118941-51028B3C-92BD-4FEF-8CC9-1E46BD6DD347
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
proteinë
@sq
proteïne in Protein tyrosine kinase 6
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
Protein tyrosine kinase 6
@en
type
label
Protein tyrosine kinase 6
@en
altLabel
PTK6 protein tyrosine kinase 6
@en
PTK6
@en
breast tumor kinase
@en
protein-tyrosine kinase 6
@en
protein-tyrosine kinase BRK
@en
tyrosine-protein kinase BRK
@en
prefLabel
Protein tyrosine kinase 6
@en
P361
P527
P637
P680
P681
P682
P352
P31
P352
P527
P637
NP_001243287
XP_016883471
P680
P681
P682
P702
P703
P705
ENSP00000217185
ENSP00000442460