about
P688
The RAD51 paralogs ensure cellular protection against mitotic defects and aneuploidyA novel role of human holliday junction resolvase GEN1 in the maintenance of centrosome integrityHuman GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctionsResolution of single and double Holliday junction recombination intermediates by GEN1.Human Holliday junction resolvase GEN1 uses a chromodomain for efficient DNA recognition and cleavage.GEN1 promotes Holliday junction resolution by a coordinated nick and counter-nick mechanism.
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in GEN1, Holliday junction 5' flap endonuclease
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
GEN1 Holliday junction 5' flap endonuclease
@en
GEN1 Holliday junction 5' flap endonuclease
@nl
type
label
GEN1 Holliday junction 5' flap endonuclease
@en
GEN1 Holliday junction 5' flap endonuclease
@nl
altLabel
GEN1
@en
Gen endonuclease homolog 1
@en
Holliday junction resolvase
@en
flap endonuclease GEN homolog 1
@en
prefLabel
GEN1 Holliday junction 5' flap endonuclease
@en
GEN1 Holliday junction 5' flap endonuclease
@nl
P361
P527
P637
P680
P681
P682
P705
P352
P31
P352
P361
P637
NP_001123481
XP_005262670
XP_006712068
XP_011531122
XP_011531123
XP_011531124
P680
P682
P702
P703
P705
ENSP00000318977
ENSP00000370653
ENSP00000433180
ENSP00000435143
ENSP00000481385