about
P688
Direct interaction between NHERF1 and Frizzled regulates β-catenin signalingModerate reduction of Norrin signaling activity associated with the causative missense mutations identified in patients with familial exudative vitreoretinopathyMutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerizationMutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathyRegulation of endothelial cell cytoskeletal reorganization by a secreted frizzled-related protein-1 and frizzled 4- and frizzled 7-dependent pathway: role in neovessel formationMutations in LRP5 or FZD4 underlie the common familial exudative vitreoretinopathy locus on chromosome 11q.A coated vesicle-associated kinase of 104 kDa (CVAK104) induces lysosomal degradation of frizzled 5 (Fzd5)Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pairSequence requirement and subtype specificity in the high-affinity interaction between human frizzled and dishevelled proteinsZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive mannerAmyloid-beta binds to the extracellular cysteine-rich domain of Frizzled and inhibits Wnt/beta-catenin signaling.A novel Wnt5a-Frizzled4 signaling pathway mediates activity-independent dendrite morphogenesis via the distal PDZ motif of Frizzled 4.Crystal structure of the Frizzled 4 receptor in a ligand-free state
P921
Q50256136-BDEF8CD0-73AB-4DE0-B561-BF94407E2961Q50272794-B34E2336-88B2-4135-93DD-400F6D595A5FQ50273600-0A28A042-96BC-48E2-A629-39CD8BE8B9FAQ50273666-E671654A-8FFA-4BEA-ABD3-C0416244040FQ50273691-735F4292-26ED-43D2-8E1C-A8F6D04F4A57Q50273699-B1C31180-6DBB-4D26-AB08-05BB773D7C00Q50275162-33BBEDBE-5F84-401B-9528-D25EC191B248Q50298828-0B9B4BC5-08E9-44A3-BE17-0B7E0F9632C9
P527
Q24298046-DA27A818-6E5E-444C-AE7B-A7F7CC80F71AQ24298412-504AD425-9533-4393-A4CC-7A8698263A99Q24302520-4FDA0057-B33F-4BA9-80BC-FA0B6C710E95Q24304241-FCB97621-33F8-4E8C-90DF-C1E5FF8A18D9Q24304483-F8513211-5272-4CC2-8274-5AE49439971DQ24317292-34CD9C83-50A2-4FFF-998A-2BE5E975F72EQ24318611-42C7466B-5BB0-4793-9A80-E376D3C37E79Q24318751-00D4FCE9-770E-4FF0-8838-E0ECFBA87BD7Q24318774-806E8909-3E28-4C2D-9DF8-1A2FCC1392D0Q24320153-5F72A4C4-F6DD-46C8-9481-6E31462EE468Q29977753-EEA2509D-A845-450F-9BB7-1CA8BF329DB5Q48447275-A5B7C2E7-2134-4AE1-8377-0B03CFC5F2AAQ57830727-4ABE5940-2C06-48A5-A548-713B32CD2F8D
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Frizzled class receptor 4
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
Frizzled class receptor 4
@en
Frizzled class receptor 4
@nl
type
label
Frizzled class receptor 4
@en
Frizzled class receptor 4
@nl
altLabel
FZD4
@en
FzE4
@en
WNT receptor frizzled-4
@en
frizzled 4, seven transmembrane spanning receptor
@en
frizzled family receptor 4
@en
frizzled homolog 4
@en
frizzled-4
@en
prefLabel
Frizzled class receptor 4
@en
Frizzled class receptor 4
@nl
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ENSP00000434034