about
P688
Function of WW domains as phosphoserine- or phosphothreonine-binding modulesThe prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau proteinPin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APCActive Mek2 as a regulatory scaffold that promotes Pin1 binding to BPGAP1 to suppress BPGAP1-induced acute Erk activation and cell migrationPin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteinsThe peptidyl-prolyl isomerase Pin1 regulates cytokinesis through Cep55The prolyl isomerase Pin1 acts as a novel molecular switch for TNF-alpha-induced priming of the NADPH oxidase in human neutrophils.Pin1 promotes degradation of Smad proteins and their interaction with phosphorylated tau in Alzheimer's disease.Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease.Pathological Role of Peptidyl-Prolyl Isomerase Pin1 in the Disruption of Synaptic Plasticity in Alzheimer's Disease.Pin1 allows for differential Tau dephosphorylation in neuronal cells.Isomerase Pin1 stimulates dephosphorylation of tau protein at cyclin-dependent kinase (Cdk5)-dependent Alzheimer phosphorylation sites.Regulation of Microtubule Assembly by Tau and not by Pin1.
P921
Q22008803-7CAA848D-6486-4A5D-B053-022F974CF384Q22010198-0E0DF93D-BA15-4763-A520-4B5D2006DA08Q24291638-4872ABFE-767F-4AFF-8AA7-ABBA7E126E23Q24300760-BDF56E63-ED80-4429-8853-93DA55BBE149Q24313316-892B3948-C1B3-4650-B20F-92DBD42C4C98Q24318424-34C76A14-D53E-4718-98D1-BB18410D4823Q34541535-35A089A3-3602-49F5-B6AA-9A9F7398C231Q35194715-A3F4BAB0-2AB8-4E28-BA69-D8114E6B20EDQ38921423-5448AAE3-2D1E-40A1-BEB5-C2DA25E4C4ACQ39757268-40C798DA-70D1-40A5-AA17-266BD7B93315Q40280535-1DDCDDF0-42F1-4DE2-8527-97EB1F5ABCBEQ41115192-ACA4CDDF-ED13-4F30-9C2B-BA02CA27872EQ46576632-00C7EF81-D20B-4386-BE22-44DC77E1AAA8
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Peptidylprolyl cis/trans isomerase, NIMA-interacting 1
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
Peptidylprolyl cis/trans isomerase, NIMA-interacting 1
@en
type
label
Peptidylprolyl cis/trans isomerase, NIMA-interacting 1
@en
altLabel
PIN1
@en
PPIase Pin1
@en
Peptidyl-prolyl cis-trans isomerase Pin1
@en
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
@en
protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
@en
protein interacting with never in mitosis A1
@en
rotamase Pin1
@en
prefLabel
Peptidylprolyl cis/trans isomerase, NIMA-interacting 1
@en
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ENSP00000247970
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