The lipid kinase phosphatidylinositol-4 kinase III alpha regulates the phosphorylation status of hepatitis C virus NS5A
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Host-Targeting Agents to Prevent and Cure Hepatitis C Virus InfectionChronic hepatitis C virus infection and lipoprotein metabolismThe yin and yang of hepatitis C: synthesis and decay of hepatitis C virus RNAAutophagy in hepatitis C virus-host interactions: potential roles and therapeutic targets for liver-associated diseasesHuman Choline Kinase-α Promotes Hepatitis C Virus RNA Replication through Modulation of Membranous Viral Replication Complex FormationInvolvement of FKBP6 in hepatitis C virus replicationA quantitative high-resolution genetic profile rapidly identifies sequence determinants of hepatitis C viral fitness and drug sensitivityVinexin β Interacts with Hepatitis C Virus NS5A, Modulating Its Hyperphosphorylation To Regulate Viral Propagation.Phosphatidylinositol 4,5-bisphosphate is an HCV NS5A ligand and mediates replication of the viral genomeA novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi.Involvement of hepatitis C virus NS5A hyperphosphorylation mediated by casein kinase I-α in infectious virus production.Kinetic analyses reveal potent and early blockade of hepatitis C virus assembly by NS5A inhibitors.Resistance patterns associated with HCV NS5A inhibitors provide limited insight into drug binding.Modulation of hepatitis C virus genome replication by glycosphingolipids and four-phosphate adaptor protein 2.Daclatasvir inhibits hepatitis C virus NS5A motility and hyper-accumulation of phosphoinositides.Genetic complementation of hepatitis C virus nonstructural protein functions associated with replication exhibits requirements that differ from those for virion assembly.Serine phosphorylation of the hepatitis C virus NS5A protein controls the establishment of replication complexes.Cyclophilin and NS5A inhibitors, but not other anti-hepatitis C virus (HCV) agents, preclude HCV-mediated formation of double-membrane-vesicle viral factoriesShould NS5A inhibitors serve as the scaffold for all-oral anti-HCV combination therapies?Several Human Liver Cell Expressed Apolipoproteins Complement HCV Virus Production with Varying Efficacy Conferring Differential Specific Infectivity to Released VirusesModulation of the Host Lipid Landscape to Promote RNA Virus Replication: The Picornavirus Encephalomyocarditis Virus Converges on the Pathway Used by Hepatitis C VirusA Proline-Tryptophan Turn in the Intrinsically Disordered Domain 2 of NS5A Protein Is Essential for Hepatitis C Virus RNA ReplicationDDX60L Is an Interferon-Stimulated Gene Product Restricting Hepatitis C Virus Replication in Cell Culture.Lipids and RNA virus replicationHepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIα to induce mitochondrial fragmentation.Mutations in Encephalomyocarditis Virus 3A Protein Uncouple the Dependency of Genome Replication on Host Factors Phosphatidylinositol 4-Kinase IIIα and Oxysterol-Binding ProteinHighlights of the Fourth Canadian Symposium on Hepatitis C: Moving towards a National Action Plan.The autophagy elongation complex (ATG5-12/16L1) positively regulates HCV replication and is required for wild-type membranous web formation.Approaches to hepatitis C treatment and cure using NS5A inhibitorsHost-targeting agents in the treatment of hepatitis C: a beginning and an end?Dengue virus- and hepatitis C virus-induced replication and assembly compartments: the enemy inside--caught in the web.Antiviral drug discovery: broad-spectrum drugs from nature.Targeting of the hydrophobic metabolome by pathogens.Phosphorylation of Serine 225 in Hepatitis C Virus NS5A Regulates Protein-Protein Interactions.Hepatitis C Virus Subverts Human Choline Kinase-α To Bridge Phosphatidylinositol-4-Kinase IIIα (PI4KIIIα) and NS5A and Upregulates PI4KIIIα Activation, Thereby Promoting the Translocation of the Ternary Complex to the Endoplasmic Reticulum for ViralSerine 235 Is the Primary NS5A Hyperphosphorylation Site Responsible for Hepatitis C Virus Replication.Foot-and-mouth disease virus replicates independently of phosphatidylinositol 4-phosphate and type III phosphatidylinositol 4-kinases.HuR Displaces Polypyrimidine Tract Binding Protein To Facilitate La Binding to the 3' Untranslated Region and Enhances Hepatitis C Virus Replication.PI4K-beta and MKNK1 are regulators of hepatitis C virus IRES-dependent translation.Entangled in a membranous web: ER and lipid droplet reorganization during hepatitis C virus infection.
P2860
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P2860
The lipid kinase phosphatidylinositol-4 kinase III alpha regulates the phosphorylation status of hepatitis C virus NS5A
description
2013 nî lūn-bûn
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2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
The lipid kinase phosphatidyli ...... atus of hepatitis C virus NS5A
@ast
The lipid kinase phosphatidyli ...... atus of hepatitis C virus NS5A
@en
The lipid kinase phosphatidyli ...... atus of hepatitis C virus NS5A
@en-gb
The lipid kinase phosphatidyli ...... atus of hepatitis C virus NS5A
@nl
type
label
The lipid kinase phosphatidyli ...... atus of hepatitis C virus NS5A
@ast
The lipid kinase phosphatidyli ...... atus of hepatitis C virus NS5A
@en
The lipid kinase phosphatidyli ...... atus of hepatitis C virus NS5A
@en-gb
The lipid kinase phosphatidyli ...... atus of hepatitis C virus NS5A
@nl
altLabel
The Lipid Kinase Phosphatidyli ...... atus of Hepatitis C Virus NS5A
@en
prefLabel
The lipid kinase phosphatidyli ...... atus of hepatitis C virus NS5A
@ast
The lipid kinase phosphatidyli ...... atus of hepatitis C virus NS5A
@en
The lipid kinase phosphatidyli ...... atus of hepatitis C virus NS5A
@en-gb
The lipid kinase phosphatidyli ...... atus of hepatitis C virus NS5A
@nl
P2093
P2860
P50
P3181
P1433
P1476
The lipid kinase phosphatidyli ...... atus of hepatitis C virus NS5A
@en
P2093
Christian Harak
Danijela Radujkovic
Ilka Rebhan
Rahel Klein
Simon Reiss
P2860
P304
P3181
P356
10.1371/JOURNAL.PPAT.1003359
P407
P577
2013-05-09T00:00:00Z