about
The lipid kinase phosphatidylinositol-4 kinase III alpha regulates the phosphorylation status of hepatitis C virus NS5APhosphorylation: the molecular switch of double-strand break repairATM-mediated phosphorylation of polynucleotide kinase/phosphatase is required for effective DNA double-strand break repairTti1 and Tel2 are critical factors in mammalian target of rapamycin complex assemblyTurning on the Radio: Epigenetic Inhibitors as Potential Radiopriming AgentsTrial Watch: Targeting ATM-CHK2 and ATR-CHK1 pathways for anticancer therapyATR-mediated regulation of nuclear and cellular plasticityRegulation of the Target of Rapamycin and Other Phosphatidylinositol 3-Kinase-Related Kinases by Membrane TargetingBeyond DNA repair: DNA-PK function in cancerAtaxia-telangiectasia: future prospectsThe expanding role of mTOR in cancer cell growth and proliferationStructure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory MechanismStructural and functional analysis of the three MIF4G domains of nonsense-mediated decay factor UPF2Saccharomyces cerevisiae Tti2 Regulates PIKK Proteins and Stress Response.The C-terminal residues of Saccharomyces cerevisiae Mec1 are required for its localization, stability, and function.The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosisAn inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cellsPI3K and cancer: lessons, challenges and opportunitiesThe Dimeric Architecture of Checkpoint Kinases Mec1ATR and Tel1ATM Reveal a Common Structural OrganizationInvestigation of the functional link between ATM and NBS1 in the DNA damage response in the mouse cerebellum.A novel mouse model for ataxia-telangiectasia with a N-terminal mutation displays a behavioral defect and a low incidence of lymphoma but no increased oxidative burden.FUS is phosphorylated by DNA-PK and accumulates in the cytoplasm after DNA damageThe versatile functions of ATM kinase.HIV-1 Nef and KSHV oncogene K1 synergistically promote angiogenesis by inducing cellular miR-718 to regulate the PTEN/AKT/mTOR signaling pathway.Two cellular protein kinases, DNA-PK and PKA, phosphorylate the adenoviral L4-33K protein and have opposite effects on L1 alternative RNA splicingMultifunctional role of ATM/Tel1 kinase in genome stability: from the DNA damage response to telomere maintenanceProtein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damageLoss of nonsense mediated decay suppresses mutations in Saccharomyces cerevisiae TRA1TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint.DNA double-strand break signaling and human disorders.The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8.Structure of the human dimeric ATM kinase.cAMP signaling inhibits radiation-induced ATM phosphorylation leading to the augmentation of apoptosis in human lung cancer cellsHIV-1 Tat promotes Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6-induced angiogenesis and tumorigenesis by regulating PI3K/PTEN/AKT/GSK-3β signaling pathwayA structural model for regulation of NHEJ by DNA-PKcs autophosphorylationReplication stress induces 53BP1-containing OPT domains in G1 cells.Choosing the right path: does DNA-PK help make the decision?Activating mutations of TOR (target of rapamycin).Resveratrol inhibits mTOR signaling by targeting DEPTOR.DNA-PKcs phosphorylates hnRNP-A1 to facilitate the RPA-to-POT1 switch and telomere capping after replication.
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Emerging common themes in regulation of PIKKs and PI3Ks
@ast
Emerging common themes in regulation of PIKKs and PI3Ks
@en
Emerging common themes in regulation of PIKKs and PI3Ks
@nl
type
label
Emerging common themes in regulation of PIKKs and PI3Ks
@ast
Emerging common themes in regulation of PIKKs and PI3Ks
@en
Emerging common themes in regulation of PIKKs and PI3Ks
@nl
prefLabel
Emerging common themes in regulation of PIKKs and PI3Ks
@ast
Emerging common themes in regulation of PIKKs and PI3Ks
@en
Emerging common themes in regulation of PIKKs and PI3Ks
@nl
P2860
P3181
P356
P1433
P1476
Emerging common themes in regulation of PIKKs and PI3Ks
@en
P2093
Thanos D Halazonetis
P2860
P304
P3181
P356
10.1038/EMBOJ.2009.281
P407
P577
2009-09-24T00:00:00Z